Results 151 to 160 of about 88,997 (296)
, 2017 Thesis (Ph.D.), Biology, Washington State UniversityAdaptation to novel and changing environmental conditions is crucial for the persistence and range expansion of species in the context of biological invasions and climate change.
Madrid Thorson, Jennifer Lorraine +1 more
core
Escherichia coli ST131: Variations on a theme of clonal expansion [PDF]
Enfermedades Infecciosas y Microbiología Clínica, 2013 Ritu, Banerjee, James R, Johnson
openaire +2 more sources
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.
With age, clonal expansions occur pervasively across normal tissues yet only in rare instances lead to cancer, despite being driven by well-established cancer drivers.
core +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Fine-scale patterns of genetic variation in a widespread clonal seagrass species
, 2016 Fine-scale patterns of genetic variation in a widespread clonal seagrass ...
TM Smith (9883070) +3 more
core
Interaction between flowering pattern and latex yield in Hevea brasiliensis Muell. Arg.
Crop Breeding and Applied Biotechnology, 2004 The interaction between flowering and latex yield was evaluated in 10 clones of Hevea brasiliensis to determine clonal stability across tapping seasons. The clones, consisting of seven clones developed in Nigeria and three imported clones, were evaluated
K. O. Omokhafe
doaj