Results 111 to 120 of about 661,172 (265)
SOX2 positively regulates tumor cell proliferation and clone formation.
, 2014 Stable transfection of SOX2 plasmid promote cell proliferation and clone formation (A) CCK8 assays in HO8910. (B) Clone formation assays in HO8910. Transient transfection of SOX2 siRNA inhibit cell proliferation and clone formation (C) CCK8 assays in ...
Youji Feng (579192) +7 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Distribution of clone numbers of each phylogenetic affiliations in each 16S rRNA gene clone library.
, 2013 Distribution of clone numbers of each phylogenetic affiliations in each 16S rRNA gene clone library.
Bin Lian (337676) +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Pages 1--25 (Preprint posted electronically on January 6, 2003)
, 2003 This paper studies methods for sequencing and mapping that rely solely on BAC pooling and shotgun sequencing. First, we scrutinize and improve the recently proposed Clone-Array Pooled Shotgun Sequencing (CAPSS) method, which delivers a clone-linked ...
Clone-Array Pooled Shotgun +2 more
core
Comparison of clone detection accuracy between DeClone and BASE in varying number of clone IDs.
, 2018 Comparison of clone detection accuracy between DeClone and BASE in varying number of clone IDs.
Hairulnizam Mahdin (4993616) +2 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2004 review of Clone Being: Exploring the Psychological and Social Dimensions, by Stephen E. Levickhttp://dx.doi.org/10.1016/S0140-6736(04)16644-
Bustillos, Dan
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source