Results 31 to 40 of about 549,061 (265)
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier +10 more
wiley +1 more source
Both rhizospheric soil microbes and shoot litter input can have profound effects on plant performance; however, their interactive effects on plants in Cd-contaminated soils remain poorly understood. We grew an invasive hyperaccumulator, Bidens pilosa, in
Xue Wang +8 more
doaj +1 more source
'There is perhaps no phenomenon in the field of biology that touches so many fundamental questions as the union of the germ cells in the act of fertilisation; in the supreme event all the strands of webs of two lives are gathered in one knot, from which they diverge again and are rewoven in a new individual life history.
openaire +2 more sources
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
Cloning and Expression of β-1, 3-1, 4-glucanase Gene from Bacillus pumilus
A gene encoding β-glucanase from Bacillus pumilus has been cloned and expressed in Escherichia coli. The whole length of the gene was 754 bp, including an ORF of 717 bp encoding 239 amino acids.
LÜ Wen-ping +4 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
VISTA in hematological malignancies: a review of the literature
In recent years, tumor immunotherapy has become an active research area, with the emergence of immune checkpoint inhibitors (ICIs) revolutionizing immunotherapy.
Yuanjia Duan +17 more
doaj +1 more source
Cloning and expression of the receptor gene (Bt-r3) of the Bt toxic protein CrylAb in E. coli
An extracellular part of the receptor gene (Bt-r3) of the Bt toxic protein Cry1Ab, with a length of about 4500 bp, was amplified by PCR and cloned into plasmid prcHis-TOPO. The recombinant plasmid pTrcHis-TOPO/peBt-r3 was transformed to E.
XU Bu-jin +4 more
doaj +1 more source
Birth of clones of the world’s first cloned dog [PDF]
AbstractAnimal cloning has gained popularity as a method to produce genetically identical animals or superior animals for research or industrial uses. However, the long-standing question of whether a cloned animal undergoes an accelerated aging process is yet to be answered. As a step towards answering this question, we compared longevity and health of
Kim, Min Jung +8 more
openaire +3 more sources

