Results 31 to 40 of about 549,061 (265)

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier   +10 more
wiley   +1 more source

Interactive effects of rhizospheric soil microbes and litter on the growth of the invasive hyperaccumulator Bidens pilosa in cadmium-contaminated soil

open access: yesFrontiers in Plant Science
Both rhizospheric soil microbes and shoot litter input can have profound effects on plant performance; however, their interactive effects on plants in Cd-contaminated soils remain poorly understood. We grew an invasive hyperaccumulator, Bidens pilosa, in
Xue Wang   +8 more
doaj   +1 more source

To clone or not to clone.

open access: yesJournal of Postgraduate Medicine, 2003
'There is perhaps no phenomenon in the field of biology that touches so many fundamental questions as the union of the germ cells in the act of fertilisation; in the supreme event all the strands of webs of two lives are gathered in one knot, from which they diverge again and are rewoven in a new individual life history.
openaire   +2 more sources

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Cloning and Expression of β-1, 3-1, 4-glucanase Gene from Bacillus pumilus

open access: yes浙江大学学报. 农业与生命科学版, 2004
A gene encoding β-glucanase from Bacillus pumilus has been cloned and expressed in Escherichia coli. The whole length of the gene was 754 bp, including an ORF of 717 bp encoding 239 amino acids.
LÜ Wen-ping   +4 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

VISTA in hematological malignancies: a review of the literature

open access: yesFrontiers in Immunology
In recent years, tumor immunotherapy has become an active research area, with the emergence of immune checkpoint inhibitors (ICIs) revolutionizing immunotherapy.
Yuanjia Duan   +17 more
doaj   +1 more source

Cloning and expression of the receptor gene (Bt-r3) of the Bt toxic protein CrylAb in E. coli

open access: yes浙江大学学报. 农业与生命科学版, 2004
An extracellular part of the receptor gene (Bt-r3) of the Bt toxic protein Cry1Ab, with a length of about 4500 bp, was amplified by PCR and cloned into plasmid prcHis-TOPO. The recombinant plasmid pTrcHis-TOPO/peBt-r3 was transformed to E.
XU Bu-jin   +4 more
doaj   +1 more source

Birth of clones of the world’s first cloned dog [PDF]

open access: yesScientific Reports, 2017
AbstractAnimal cloning has gained popularity as a method to produce genetically identical animals or superior animals for research or industrial uses. However, the long-standing question of whether a cloned animal undergoes an accelerated aging process is yet to be answered. As a step towards answering this question, we compared longevity and health of
Kim, Min Jung   +8 more
openaire   +3 more sources

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