Results 51 to 60 of about 532,228 (303)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

On Node Replication Attack in Wireless Sensor Networks [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2016
WSNs (Wireless Sensor Networks) comprise a large number of small, inexpensive, low power and memory constrained sensing devices (called sensor nodes) that are densely deployed to measure a given physical phenomenon.
Mumtaz Qabulio   +2 more
doaj  

MHC class II regulation of CD8+ T cell tolerance and implications in autoimmunity and cancer immunotherapy

open access: yesCell Reports, 2023
Summary: Major histocompatibility complex (MHC) class II-reactive CD8+ T cells are found in humans and animals, but little is known about their identity, development, and function.
Xiaojuan Zhou   +17 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Oligogalacturonide-Mediated Induction of a Gene Involved in Jasmonic Acid Synthesis in Response to the Cell-Wall-Degrading Enzymes of the Plant Pathogen Erwinia carotovora

open access: yesMolecular Plant-Microbe Interactions, 1999
Identification of Arabidopsis thaliana genes responsive to plant cell-wall-degrading enzymes of Erwinia carotovora subsp. carotovora led to the isolation of a cDNA clone with high sequence homology to the gene for allene oxide synthase, an enzyme ...
Cecilia Norman   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Attack of the clones: an investigation into removing redundant source code [PDF]

open access: yes, 2002
Long-term maintenance of code will often lead to the introduction of duplicated or 'cloned' code. Legacy systems riddled with these clones have large amounts of redundant code and are more difficult to understand and maintain.
Bailey, John Oliver
core  

Clone wars: Distributed detection of clone attacks in mobile WSNs

open access: yesJournal of Computer and System Sciences, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mauro Conti   +2 more
openaire   +4 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reaction of transgenic plum cv. HoneySweet to the Plum pox virus after a severe infection of Monilinia sp. - short communication

open access: yesPlant Protection Science, 2019
Resistance to Plum pox virus (PPV) in transgenic Prunus domestica L., clone C5 (cv. HoneySweet) was evaluated in a regulated field in the Czech Republic for fifteen years (2002-2016). PPV mild symptoms appeared in C5 trees only in several leaves situated
Jaroslav Polák   +3 more
doaj   +1 more source

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