Results 221 to 230 of about 3,181,244 (296)

Protocol for single-cell epigenetic profiling in human organoids and tumoroids with Epi-CyTOF. [PDF]

STAR Protoc
Senoglu E, Mittné V, Dietz S, Eugster A, Thieme S, Baenke F, Albert M, Peitzsch C.   +7 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Machine Learning of Personal Repertoires From Public T Cell Receptors. [PDF]

Immunol Rev
Malca O, Zilberberg A, Efroni S.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A scalable, dividing cell model for the robust propagation and quantification of human sporadic Creutzfeldt-Jakob disease prions. [PDF]

Proc Natl Acad Sci U S A
Nihat A, Arora P, Schmidt C, Rayner MLD, Linehan J, Brandner S, Mead S, Collinge J, Jat PS.   +8 more
europepmc   +1 more source

Strategies for clone detection, selection and isolation in Per.C6 cells - case for Rebmab100 [PDF]

BMC Proc, 2013
Yeda F, dos Santos M, Tsuruta L, Horta B, Inocencio A, Okamoto O, Tuma M, Moro A.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Clonal hematopoiesis in Alzheimer's brain: Protective, pathogenic, and context-dependent? [PDF]

Trends Mol Med
Zhao H, King KY, Wong ST.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Molecular Characterization of a Novel Monopartite Begomovirus Infecting Weeds and Important Crops in Yunnan, China. [PDF]

Viruses
Zhao L, Zhong J, Zhang S, Li T, Yin Y, Dong R, Ding M.   +6 more
europepmc   +1 more source