Results 181 to 190 of about 47,030 (222)
Intraoperative Clonidine in Spine Surgery: A Randomised Controlled Trial. [PDF]
Acta Anaesthesiol ScandBirkebæk S +4 more
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Advances in Alcohol & Substance Abuse, 1988
Clonidine has provided a nonaddicting solution to an ancient problem, opiate withdrawal without opiates. Gold and colleagues' initial demonstration that this alpha 2 adrenergic agonist could be used to detoxify opiate addicts provided the first nonaddicting treatment for opiate dependency.
H, Roehrich, M S, Gold
openaire +3 more sources
Clonidine has provided a nonaddicting solution to an ancient problem, opiate withdrawal without opiates. Gold and colleagues' initial demonstration that this alpha 2 adrenergic agonist could be used to detoxify opiate addicts provided the first nonaddicting treatment for opiate dependency.
H, Roehrich, M S, Gold
openaire +3 more sources
Pediatrics, 1976
Clonidine (Catapres, Boehringer Ingelheim) is a relatively new hypotensive agent with complex pharmacologic actions on the autonomic nervous system. Little is known about its effects and side effects in children. An interesting combination of these were seen in a child who accidentally ingested an unknown quantity of this drug.
G S, Pai, D J, Lipsitz
openaire +2 more sources
Clonidine (Catapres, Boehringer Ingelheim) is a relatively new hypotensive agent with complex pharmacologic actions on the autonomic nervous system. Little is known about its effects and side effects in children. An interesting combination of these were seen in a child who accidentally ingested an unknown quantity of this drug.
G S, Pai, D J, Lipsitz
openaire +2 more sources
Critical Care Medicine, 1983
A case of acute intoxication in a 60-yr-old woman who ingested 20 mg of clonidine is presented. The patient showed CNS depression (bradycardia, hypotonia) with systemic hypertension and peripheral vasoconstriction. She was treated with atropine and sodium nitroprusside. There was no recurrence and the patient recovered in 8 days.
L, Marruecos +3 more
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A case of acute intoxication in a 60-yr-old woman who ingested 20 mg of clonidine is presented. The patient showed CNS depression (bradycardia, hypotonia) with systemic hypertension and peripheral vasoconstriction. She was treated with atropine and sodium nitroprusside. There was no recurrence and the patient recovered in 8 days.
L, Marruecos +3 more
openaire +2 more sources
2023
Abstract Clonidine’s molecular mechanism of action is agonism at the alpha-2A receptor, a subtype of the alpha-2-adrenergic receptor, found principally within the prefrontal cortex (PFC), where it prevents the secretion of norepinephrine (NE). NE causes the symptoms of withdrawal.
Mark S. Gold, Kenneth Blum
openaire +1 more source
Abstract Clonidine’s molecular mechanism of action is agonism at the alpha-2A receptor, a subtype of the alpha-2-adrenergic receptor, found principally within the prefrontal cortex (PFC), where it prevents the secretion of norepinephrine (NE). NE causes the symptoms of withdrawal.
Mark S. Gold, Kenneth Blum
openaire +1 more source