Results 131 to 140 of about 7,941 (270)
We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang+13 more
wiley +1 more source
Artificial intelligence-driven circRNA vaccine development: multimodal collaborative optimization and a new paradigm for biomedical applications. [PDF]
Zhao Y, Wang H.
europepmc +1 more source
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma+9 more
wiley +1 more source
Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications. [PDF]
Kim H+17 more
europepmc +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels+7 more
wiley +1 more source
Quantum-inspired logic for advanced Transcriptional Programming. [PDF]
Milner PT, Kim D, Wilson CJ.
europepmc +1 more source
Evidence that macrophages are programmed to die after activating autologous, cloned, antigen-specific, CD4 + T cells [PDF]
Bruce C. Richardson+3 more
openalex
Transcript Identification Using Arrayed Hydrogels With TrapFISH
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse+5 more
wiley +1 more source