Results 141 to 150 of about 7,941 (270)

Facile Fabrication of Large‐Area Biofunctionalized Metallic Nanostructures for High Performance Affinity Plasmonic Biosensors

open access: yesAdvanced Materials Technologies, EarlyView.
A novel approach enables facile and reproducible fabrication of gold nanoparticle arrays with tunable near‐infrared plasmonic properties and enhanced sensing accuracy. Using advanced lithography and ion milling, combined with innovative surface chemistry, the approach minimizes ohmic losses and non‐specific sorption, improving biomolecular detection ...
Dario Cattozzo Mor   +12 more
wiley   +1 more source

CRISPR-BEasy: a free web-based service for designing sgRNA tiling libraries for CRISPR-dependent base editing screens. [PDF]

open access: yesNucleic Acids Res
Chapdelaine-Trépanier V   +9 more
europepmc   +1 more source

Stable Imitation of Multigait and Bipedal Motions for Quadrupedal Robots Over Uneven Terrains

open access: yesAdvanced Robotics Research, EarlyView.
How are quadrupedal robots empowered to execute complex navigation tasks, including multigait and bipedal motions? Challenges in stability and real‐world adaptation persist, especially with uneven terrains and disturbances. This article presents an imitation learning framework that enhances adaptability and robustness by incorporating long short‐term ...
Erdong Xiao   +3 more
wiley   +1 more source

High-throughput screening of human genetic variants by pooled prime editing. [PDF]

open access: yesCell Genom
Herger M   +5 more
europepmc   +1 more source

Diagnostic utility of programmed cell death ligand 1 (clone SP142) immunohistochemistry for malignant lymphoma and lymphoproliferative disorders: A brief review

open access: gold, 2021
Ayako Sakakibara   +13 more
openalex   +2 more sources

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

open access: yesAdvanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen   +2 more
wiley   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu   +14 more
wiley   +1 more source

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