Results 151 to 160 of about 7,941 (270)
Detecting Refactorable Clones by Slicing Program Dependence Graphs
Code duplication in a program can make understanding and maintenance difficult. The problem can be reduced by detecting duplicated code, refactoring it into a separate procedure, and replacing all the clones by appropriate calls to the new procedure.
Hamid, A., Zaytsev, V.
openaire +1 more source
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville+6 more
wiley +1 more source
Methyltransferase Domain-Focused Genome Mining for Fungal Polyketide Synthases. [PDF]
Yan D, Matsuda Y.
europepmc +1 more source
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang+14 more
wiley +1 more source
How many plasmids can bacteria carry? A synthetic biology perspective. [PDF]
Kiattisewee C.
europepmc +1 more source
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source
Programming anti-ribozymes to sense trigger RNAs for modulating gene expression in mammalian cells. [PDF]
Zhang W+5 more
europepmc +1 more source
EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li+15 more
wiley +1 more source