Results 231 to 240 of about 6,692,619 (327)

Data‐Driven Bulldozer Blade Control for Autonomous Terrain Leveling

open access: yesAdvanced Robotics Research, EarlyView.
A simulation‐driven framework for autonomous bulldozer leveling is presented, combining high‐fidelity terramechanics simulation with a neural‐network‐based reduced‐order model. Gradient‐based optimization enables efficient, low‐level blade control that balances leveling quality and operation time.
Harry Zhang   +5 more
wiley   +1 more source

Abstraction hierarchy to define biofoundry workflows and operations for interoperable synthetic biology research and applications. [PDF]

open access: yesNat Commun
Kim H   +17 more
europepmc   +1 more source

Sequential expression of new gene programs in inducer T-cell clones.

open access: green, 1983
Gordon J. Freeman   +4 more
openalex   +2 more sources

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Specific killing and resensitization of pathogenic Escherichia coli strains carrying blaCTX-M-15 β-lactamase using targeted-antibacterial-plasmids (TAPs). [PDF]

open access: yesNucleic Acids Res
Derollez E   +11 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

Quantum cryptography integrating an optical quantum memory. [PDF]

open access: yesSci Adv
Mamann H   +8 more
europepmc   +1 more source

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