Results 31 to 40 of about 47,712 (289)

ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data

open access: yesBMC Bioinformatics, 2010
Background Chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing (ChIP-seq) or ChIP followed by genome tiling array analysis (ChIP-chip) have become standard technologies for genome-wide identification of DNA-binding protein target ...
Pagès Hervé   +6 more
doaj   +1 more source

New transposon tools tailored for metabolic engineering of Gram-negative microbial cell factories

open access: yesFrontiers in Bioengineering and Biotechnology, 2014
Re-programming microorganisms to modify their existing functions and/or to bestow bacteria with entirely new-to-Nature tasks have largely relied so far on specialized molecular biology tools.
Esteban eMartínez-García   +3 more
doaj   +1 more source

Transforming quantum operations: quantum supermaps

open access: yes, 2008
We introduce the concept of quantum supermap, describing the most general transformation that maps an input quantum operation into an output quantum operation.
Chiribella G. D'Ariano G. M. Perinotti P.   +10 more
core   +1 more source

Optimal and covariant single-copy LOCC transformation between two two-qubit states [PDF]

open access: yes, 2006
Given two two-qubit pure states characterized by their Schmidt numbers we investigate an optimal strategy to convert the states between themselves with respect to their local unitary invariance.
Bengtsson   +33 more
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A biometric and PUF-based authentication with Preserving anonymity in smart grid environment

open access: yesAin Shams Engineering Journal
The intelligent grid environment is an electricity transmission and distribution system utilizing information and communication technology with two main components: the Smart Meter (SM) and the Service Provider (SP).
E. Haodudin Nurkifli
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy