Results 61 to 70 of about 47,712 (289)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Cloning the entanglement of a pair of quantum bits

, 2003
It is shown that any quantum operation that perfectly clones the entanglement of all maximally-entangled qubit pairs cannot preserve separability. This ``entanglement no-cloning'' principle naturally suggests that some approximate cloning of entanglement
Jaromír Fiurášek, Louis-Philippe Lamoureux, M. A. Nielsen, N. J. Cerf, Nicolas J. Cerf, Patrick Navez, W. K. Wootters   +6 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Swarm, genetic and evolutionary programming algorithms applied to multiuser detection

Semina: Ciências Exatas e Tecnológicas, 2005
In this paper, the particles swarm optimization technique, recently published in the literature, and applied to Direct Sequence/Code Division Multiple Access systems (DS/CDMA) with multiuser detection (MuD) is analyzed, evaluated and compared.
Paul Jean Etienne Jeszensky, Leonardo Dagui de Oliveira, Taufik Abrão, Fernando Ciriaco   +3 more
doaj  

Hepatocellular Carcinoma Mechanisms Associated with Chronic HCV Infection and the Impact of Direct-Acting Antiviral Treatment

Journal of Hepatocellular Carcinoma, 2020
Srikanta Dash,1– 3 Yucel Aydin,1 Kyle E Widmer,2 Leela Nayak2 1Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA; 2Southeast Louisiana Veterans Health Care System, New Orleans, LA ...
Dash S, Aydin Y, Widmer KE, Nayak L
doaj  

Probabilistic cloning and identification of linearly independent quantum states

, 1998
We construct a probabilistic quantum cloning machine by a general unitary-reduction operation. With a postselection of the measurement results, the machine yields faithful copies of the input states.
A. Ekert, A. Peres, C. H. Bennett, C. H. Bennett, C. H. Bennett, C. H. Bennett, C. W. Helstrom, D. Dieks, D. Dieks, D. Mozyrsky, G. Jaeger, G. M. D'Ariano, Guang-Can Guo, H. Barnum, H. P. Yuen, K. Kraus, Lu-Ming Duan, M. A. Nielsen, M. Brune, M. Hillery, N. Gisin, N. Gisin, S. M. Barnett, V. Buzek, V. Buzek, W. K. Wootters   +25 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Visual Cloning 2000: a DNA sequence analysis program.

Journal of molecular microbiology and biotechnology, 2002
VC2000 is a recommendable, easy-to-use and affordable program suited particularly to plot maps of both plasmids and linear DNA fragments for the documentation of cloning procedures. It comes with basic tools for sequence analysis that assist this major utility. A special feature of the program is the integration of web-based tools, providing additional
Kusian, Bernhard, Bowien, Botho
openaire   +2 more sources

An Example of Cloning Graph Transformation Rules for Programming

Electronic Notes in Theoretical Computer Science, 2008
AbstractGraphical notations are already popular for the design of software, as witnessed by the success of the Uniform Modeling Languages (UML). In this paper, we advocate the use of graphs and graph transformation for programming graph-based systems. Our case study, the flattening of hierarchical statecharts, reveals that cloning, a recently proposed ...
Minas, Mark, Hoffmann, Berthold
openaire   +1 more source