Results 81 to 90 of about 47,712 (289)
A Step-indexed Semantics of Imperative Objects
Step-indexed semantic interpretations of types were proposed as an alternative to purely syntactic proofs of type safety using subject reduction. The types are interpreted as sets of values indexed by the number of computation steps for which these ...
Benjamin Pierce +2 more
core +6 more sources
The Program with a Personality: Analysis of Elk Cloner, the First Personal Computer Virus [PDF]
Scott Levy, Jedidiah R. Crandall
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
'TV Format Protection through Marketing Strategies?' [PDF]
Commercially successful programme ideas are often imitated or adapted. Television formats, in particular, are routinely copied. Starting from radio formats in the 1950s to game shows and reality programme formats of today, producers have accused others ...
Singh, Sukhpreet
core
Promoter Cloning of Human SETDB1 Gene Utilizing Bioinformatic Programs
Eukaryotic gene expression is an important process, which is initiated by several transcription factors and RNA polymerases that occupy the promoter region of genomic DNA. Although there are many experiments to identify the promoter region in a gene, it is time and labor consuming to finalize it.
Hee-Jung Noh, Keun-Cheol Kim
openaire +2 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The Efficiency of Clonal Selection as A Breeding Program to Improve Chinese Garlic Cultivar (Allium sativum L.) [PDF]
E. Helmy, Entsar Ragheb
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Linear-algebraic lambda-calculus
With a view towards models of quantum computation and/or the interpretation of linear logic, we define a functional language where all functions are linear operators by construction.
Arrighi, Pablo, Dowek, Gilles
core +1 more source

