Results 81 to 90 of about 6,692,619 (327)
Search of clones in program code [PDF]
Scientific and Technical Journal of Information Technologies, Mechanics and Optics, 2020 A.O. Osadchaya, I.V. Isaev
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Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Kevoree Modeling Framework (KMF): Efficient modeling techniques for runtime use [PDF]
, 2014 The creation of Domain Specific Languages(DSL) counts as one of the main goals in the field of Model-Driven Software Engineering (MDSE). The main purpose of these DSLs is to facilitate the manipulation of domain specific concepts, by providing developers
Barais, Olivier +6 more
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A lambda calculus for quantum computation with classical control
, 2004 The objective of this paper is to develop a functional programming language for quantum computers. We develop a lambda calculus for the classical control model, following the first author's work on quantum flow-charts.
A. Tonder +8 more
core +3 more sources
CLONE 3: plasmid drawing and clone management software program for microcomputers.
BioTechniques, 1990 CLONE 3 is a microcomputer software program which draws circular and linear plasmid maps, facilitates cloning operations and performs related sequence analysis and information retrieval functions. This article describes the use of the CLONE 3 program to streamline the flow of information in the research laboratory doing genetic engineering applications.
E A, Peterson, D F, Ward
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Conceptual Spaces in Object-Oriented Framework [PDF]
, 2016 The aim of this paper is to show that the middle level of mental representations in a conceptual spaces framework is consistent with the OOP paradigm.
Gemel, Aleksander, Ishii, Tadao
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The Myogenesis Program Drives Clonal Selection and Drug Resistance in Rhabdomyosarcoma [PDF]
, 2021 Anand G. Patel +19 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source