Clonorchis sinensis infection contributes to hepatocellular carcinoma progression via enhancing angiogenesis [PDF]
PLoS Neglected Tropical DiseasesBackgroundClonorchis sinensis (C. sinensis) infection plays an important role in the progression of hepatocarcinogenesis. However, its specific role in HCC progression remains unclear. This study aimed to investigate whether C.
Yuling Qin, Qiumei Lin, Zeli Tang
exaly +4 more sources
Cholecystolithiasis Is Associated with Clonorchis sinensis Infection [PDF]
PLoS ONE, 2012 BACKGROUND: The objective of this study was to analyze gallbladder stones for direct evidence of a relationship between Clonorchis sinensis infection and gallbladder stones formation.
Tie Qiao, Xiao-Bing Luo
exaly +2 more sources
Ivermectin Identified Using a High-Throughput Screening System Exhibits Anti-Clonorchis sinensis Activity in Rats [PDF]
AntibioticsBackground: Clonorchiasis, caused by the parasite Clonorchis sinensis, remains a public health concern in East Asian countries. Methods: In this study, high-throughput screening was used to analyze 320 compounds for potential inhibitory activity against ...
Soon-Ok Lee +7 more
doaj +2 more sources
Clonorchis sinensis promotes hepatocellular carcinoma progression via a potential PTTG1-β-catenin-c-MYC axis [PDF]
Food and Waterborne ParasitologyClonorchis sinensis (C. sinensis) infection is a recognized risk factor for hepatocellular carcinoma (HCC) and is linked to poor overall survival. To explore the underlying mechanisms, RNA sequencing was conducted on HCC tissues from C. sinensis-positive
Tai-Xin Yang +15 more
doaj +2 more sources
Multiparasitism in Spain in a Korean Visiting Friends and Relatives: Case Report and Review of Imported Cases of Clonorchis sinensis in Europe [PDF]
Clinical Case ReportsWe report a case of imported Clonorchis sinensis infection under the modality of “visiting friends and relatives.” Clonorchis was not diagnosed initially, and a second stool sample was necessary.
Paola Cociancic +2 more
doaj +2 more sources
PLoS Neglected Tropical DiseasesBackgroundExtensive evidence links Clonorchis sinensis (C. sinensis) to cholangiocarcinoma; however, its association with hepatocellular carcinoma (HCC) is less acknowledged, and the underlying mechanism remains unclear.
Qiumei Lin, Zeli Tang, Yuling Qin
exaly +2 more sources
Identification of Clonorchis sinensis in bronchoalveolar lavage fluid and peripheral blood using next-generation sequencing in a patient with septic shock: a case report and literature review [PDF]
Emerging Microbes and InfectionsWe present a case report of a 59-year-old male diagnosed with pancreatic cancer with multiple abdominal metastases, in whom metagenomic next-generation sequencing unexpectedly identified Clonorchis sinensis genomic sequences in both bronchoalveolar ...
Weipeng Liu +5 more
doaj +2 more sources
Clonorchis sinensis infection remodels chromatin accessibility in hepatocellular carcinoma [PDF]
Parasites & VectorsBackground Hepatocellular carcinoma (HCC) is a major global health concern, accounting for a significant proportion of liver cancer cases and related deaths. Clonorchis sinensis (C. sinensis) infection, a recognized carcinogen, has been implicated in the
Weilong Yang +9 more
doaj +2 more sources
PLoS Neglected Tropical DiseasesBackgroundWe examined the impact of the Clonorchis sinensis (C. sinensis) infection on the survival outcomes of spontaneous rupture Hepatocellular Carcinoma (srHCC) patients undergoing hepatectomy.MethodsBetween May 2013 and December 2021, 157 ...
Zhan Lu, Bang-De Xiang
exaly +2 more sources
Unexpected discovery of Clonorchis sinensis by common bile duct exploration
Clinical Case Reports, 2022 Coexisting choledocholithiasis and Clonorchis sinensis infection are relatively rare. We report a 39‐year‐old patient with choledocholithiasis who inadvertently found Clonorchis sinensis during common bile duct exploration.
Ping Shao, Qing Chen
doaj +1 more source