Results 111 to 120 of about 11,264,159 (286)

Tuning VSV-G Expression Improves Baculovirus Integrity, Stability and Mammalian Cell Transduction Efficiency

Viruses
Baculoviral vectors (BVs) derived from Autographa californica multiple nucleopolyhedrovirus (AcMNPV) are an attractive tool for multigene delivery in mammalian cells, which is particularly relevant for CRISPR technologies.
Martina Mattioli, Renata A. Raele, Gunjan Gautam, Ufuk Borucu, Christiane Schaffitzel, Francesco Aulicino, Imre Berger   +6 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Risk Screening Tools Could Potentially Miss HIV-Positive Individuals Who Seek Testing Services: A Secondary Program Data Analysis on the Performance Characteristics of an Adolescent and Adult HIV Risk Screening Tool in Uganda

Tropical Medicine and Infectious Disease
Improving HIV testing efficiency saves financial and material resources for health. We conducted a secondary data analysis of routinely collected HIV risk-screening program data in Uganda, from October to November 2019, to determine the performance ...
Marvin Lubega, Katherine Guerra, Megan Ginivan, Yewande Kamuntu, George Senyama, Andrew Musoke, Fiona Gambanga, Shaukat Khan, Geoffrey Taasi, Sylivia Nalubega, John Bosco Junior Matovu   +10 more
doaj   +1 more source

Epsilon Indi Ba/Bb: the nearest binary brown dwarf

, 2003
We have carried out high angular resolution near-infrared imaging and low-resolution (R~1000) spectroscopy of the nearest known brown dwarf, Eps Indi B, using the ESO VLT NAOS/CONICA adaptive optics system.
Artigau, B. Biller, Baraffe, Bouy, Burgasser, Burgasser, Burgasser, Burrows, Chabrier, Close, Close, Close, Cushing, Dahn, Geballe, Geballe, Geballe, Gizis, Goto, Hambly, Hambly, Kirkpatrick, L. M. Close, Lachaume, Leggett, M. Hartung, M. J. McCaughrean, Maiolino, Martín, McLean, N. Lodieu, Nakajima, Potter, R. Lenzen, R.-D. Scholz, Reid, Scholz, Volk, W. Brandner   +38 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Estimation of Daytime NO3 Radical Levels in the UK Urban Atmosphere Using the Steady State Approximation Method

Advances in Meteorology, 2015
The steady state approximation has been applied to the UK National Environment Technology Centre (NETCEN) data at three urban sites in the UK (Marylebone Road London, London Eltham, and Harwell) over the period of 1997 to 2012 to estimate the ...
M. A. H. Khan, W. C. Morris, L. A. Watson, M. Galloway, P. D. Hamer, B. M. A. Shallcross, C. J. Percival, D. E. Shallcross   +7 more
doaj   +1 more source

Close-packed dimers on nonorientable surfaces

, 2001
The problem of enumerating dimers on an M x N net embedded on non-orientable surfaces is considered. We solve both the Moebius strip and Klein bottle problems for all M and N with the aid of imaginary dimer weights.
Blöte, F.Y. Wu, Fisher, Gradshteyn, Kaneda, Kasteleyn, Lu, Lu, McCoy, Propp, Shrock, Stanley, Temperley, Tesler, Tzeng, Wentao T. Lu, Wu   +16 more
core   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Magnetically warped discs in close binaries

, 2002
We demonstrate that measurable vertical structure can be excited in the accretion disc of a close binary system by a dipolar magnetic field centred on the secondary star.
Applegate, Bianchini, Billington, Dalia Chakrabarty, Graham A. Wynn, Howell, James R. Murray, King, King, Kraft, Lai, Larwood, Louisa Kramer, Lubow, Lubow, Lubow, Mestel, Murray, Murray, Murray, Murray, Murray, Murray, Nelson, Nelson, O'Donoghue, Ogilvie, Papaloizou, Patterson, Patterson, Patterson, Pearson, Pringle, Rolfe, Skumanich, Terquem, Truss, Verbunt, Warner, Wood, Yukawa   +40 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source