Results 191 to 200 of about 11,282,248 (285)

Phase Engineering of Nanogold: Non-Close Packed Square Planes in A'B' Stacking with a 0.5 Å Channel. [PDF]

Adv Mater
Wang Y, Liu Z, Gianopoulos CG, Zhang W, Alfonso D, He G, Kirschbaum K, Zhou M, Jin R.   +8 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The blur paradox: Better recognition at a distance. [PDF]

J Vis
Long C, Yuan L, Wu C, Oruc I.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The relative contribution of close-proximity contacts, shared classroom exposure and indoor air quality to respiratory virus transmission in schools. [PDF]

Nat Commun
Banholzer N, Munday JD, Jent P, Bittel P, Dall'Amico L, Furrer L, Bürki C, Stadler T, Egger M, Hascher T, Cattuto C, Fenner L.   +11 more
europepmc   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Author Correction: Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

Nature Communications
David P. Tilly, Jean-Paul Heeb, Simon J. Webb, Jonathan Clayden   +3 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Correction: Global analysis of carbon disulfide (CS₂) using the 3-D chemistry transport model STOCHEM. AIMS Environ Sci 4: 484-501

AIMS Environmental Science, 2017
Anwar Khan, Benjamin Razis, Simon Gillespie, Carl Percival, Dudley Shallcross   +4 more
doaj   +1 more source

Decoding dog communication through the physiology and behavior of urine marking. [PDF]

Sci Rep
Quaranta A, d'Ingeo S, Minunno M, Straziota V, Nolè M, Ventriglia G, Ceci E, Siniscalchi M.   +7 more
europepmc   +1 more source