Results 51 to 60 of about 507,473 (299)

Closed-Form Solutions and Conserved Vectors of a Generalized (3+1)-Dimensional Breaking Soliton Equation of Engineering and Nonlinear Science

Mathematics, 2020
In this article, we examine a (3+1)-dimensional generalized breaking soliton equation which is highly applicable in the fields of engineering and nonlinear sciences.
Chaudry Masood Khalique, Oke Davies Adeyemo   +1 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Two identities and closed-form formulas for the Bernoulli numbers in terms of central factorial numbers of the second kind

Demonstratio Mathematica, 2022
In this article, the authors present two identities involving products of the Bernoulli numbers, provide four alternative proofs for these two identities, derive two closed-form formulas for the Bernoulli numbers in terms of central factorial numbers of ...
Chen Xue-Yan, Wu Lan, Lim Dongkyu, Qi Feng   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A Closed-Form Buckling Formula for Open-Coiled and Properly Supported Circular-Bar Helical Springs

Journal of Mechanical Engineering, 2018
As a continuation of the author’s previous studies on the buckling analysis of helical springs, a closed-form formula having been obtained with the help of the artificial neural network (ANN) is proposed and discussed in detail for the first time for a ...
Vebil Yildirim
doaj   +1 more source

Joshi’s Split Tree for Option Pricing

Risks, 2020
In a thorough study of binomial trees, Joshi introduced the split tree as a two-phase binomial tree designed to minimize oscillations, and demonstrated empirically its outstanding performance when applied to pricing American put options.
Guillaume Leduc, Merima Nurkanovic Hot
doaj   +1 more source

Variance Swap Pricing under Markov-Modulated Jump-Diffusion Model

Discrete Dynamics in Nature and Society, 2021
This paper investigates the pricing of discretely sampled variance swaps under a Markov regime-switching jump-diffusion model. The jump diffusion, as well as other parameters of the underlying stock’s dynamics, is modulated by a Markov chain representing
Shican Liu, Yu Yang, Hu Zhang, Yonghong Wu   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Note on a discrete initial value problem from a competition

Advances in Difference Equations, 2021
The following discrete initial value problem x n + 1 = x n ( x n − 1 2 − 2 ) − x 1 , n ∈ N , $$ x_{n+1}=x_{n}\bigl(x_{n-1}^{2}-2 \bigr)-x_{1},\quad n\in {\mathbb{N}}, $$ x 0 = 2 $x_{0}=2$ and x 1 = 5 / 2 $x_{1}=5/2$ , appeared at an international ...
Stevo Stević
doaj   +1 more source

A closed-form pricing formula for European options under the Heston model with stochastic interest rate

Journal of Computational and Applied Mathematics, 2018
In this paper, a closed-form pricing formula for European options in the form of an infinite series is derived under the Heston model with the interest rate being another random variable following the CIR (Cox–Ingersoll–Ross) model.
Xin‐Jiang He, Song‐Ping Zhu
semanticscholar   +1 more source