Results 151 to 160 of about 175,978,596 (203)

Fail-Closed Validation of Lineage-Associated Transcript-Count Diversity After IFN-β Stimulation in a Public Human PBMC Dataset. [PDF]

Int J Mol Sci
Quiroz RN, Lindo KE, Pinilla AJ, Díaz-Olmos Y, Fernández-Ponce C, Peñata EZ, Bello Lemus Y, Lugo LP, Londoño LP, Acosta Hoyos A, Freyle NG, Chamorro KER, Villarreal-Camacho JL, Navarro Quiroz E.   +13 more
europepmc   +1 more source

Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph, Megan McCune, Riley Bove, Ahmed Abdelhak, Bruce A. C. Cree, Valerie J. Block   +5 more
wiley   +1 more source

X-THREAT framework for adaptive and explainable deep learning-based minority-class and zero-day cyber threat detection. [PDF]

Sci Rep
Qaisarani SN, Badri SK, Khattak A, Alghazzawi DM, Alghamdi MY, Alkhozae M, Almakky A, Alhazmi RM, Asghar MZ.   +8 more
europepmc   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Trust-gated synthetic EEG augmentation reduces performance drops when generalizing to new patients. [PDF]

NPJ Digit Med
Choi D, Yip C, Choi A, Park J.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Comprehensive benchmarking and explainable machine learning analysis of EEG imagery activity recognition. [PDF]

Sci Rep
Siam MJN, Showrov TA, Hossain MS, Ayaan NS, Bari SMS, Tariq F, Mahmud AA.   +6 more
europepmc   +1 more source

Incident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population‐Based Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the incidence of diabetes mellitus and its associations with hospitalisation and mortality in adults with multiple sclerosis (MS) and matched controls. Methods Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 ...
Yolanda Lau, Sedigheh Zabihi, Morghan Hartmann, Georgina Mathlin, Sube Banerjee, Ebaa Marouf, Clare Hadley, Claudia Cooper, Ruth Dobson   +8 more
wiley   +1 more source

Artificial intelligence-enhanced management system for secondary prevention of coronary heart disease: a randomized clinical trial. [PDF]

BMC Med
Ba Z, Yuan J, Zhao S, Liu M, Chen G, Lian X, Yu F, Su Y, Wang Z, Yang L, Wang X, Wang Y, Zhang X, Zhao W, Gao X, Wu Y.   +15 more
europepmc   +1 more source