Results 81 to 90 of about 2,722 (215)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Closed Form Solution for Partial Interaction of Composite Reinforced Concrete Beams
Journal of Engineering and Sustainable Development, 2008 An analytical method for the elastic analysis of the interaction between a reinforced concrete beam and a steel plate bonded to it by flexible connectors is presented. The shear distributed force is formulated.
Hanadi F. Naji +2 more
doaj
Solution of the non-local problem for the hyperbolic equation in the closed form
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2007 The non-local boundary value problem for the degenerate hyperbolic equation in the area D, which is the union of two areas in the upper and lower half-planes, is examined.
R. N. Salikhov
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Croatian Operational Research ReviewThis paper provides an economic and mathematical analysis of the long-run profit maximization problem of a monopolist with linear demand and a two-input Cobb-Douglas technology to derive the conditions that guarantee the solution to this problem.
Zrinka Lukač, Mira Krpan, Vedran Kojić
doaj +1 more source
Solvable subclasses of a class of nonlinear second-order difference equations
Advances in Nonlinear Analysis, 2016 We present some solvable subclasses of the class of nonlinear second-order difference equations of the form Axn+1 + Bxn+1xn + Cxnxn-1 + Gxn+1xn-1 + Dxn + Exn-1 + F = 0, n ∈ ℕ0, where the parameters A, B, C, D, E, F, G and the initial values x-1,x0 are ...
Stević Stevo
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source