Results 131 to 140 of about 278,450 (300)

Closed-loop Koopman operator approximation

open access: yesMachine Learning: Science and Technology
This paper proposes a method to identify a Koopman model of a feedback-controlled system given a known controller. The Koopman operator allows a nonlinear system to be rewritten as an infinite-dimensional linear system by viewing it in terms of an ...
Steven Dahdah, James Richard Forbes
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

A quasi-closed-loop control strategy for efficiency-oriented DC–DC converters under mixed steady-state and transient conditions

open access: yesEnergy Conversion and Management: X
This paper proposes a quasi-closed-loop control strategy for DC-DC converters to achieve improved power efficiency while maintaining dynamic response. The proposed approach allows the converter to operate in open-loop mode under steady-state conditions ...
Wei Jiang   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Closed-Loop Recyclable Vinylogous Carbamothioate-Based Covalent Adaptable Networks

open access: yes
Synthesis of covalent adaptable networks (CANs) has been considered a promising strategy to address the challenge of recycling thermosets. However, there is still huge room for improvement, such as diversity of polymer networks, closed-loop recycling ...
Zheng-Hong Luo (1493296)   +4 more
core   +1 more source

A Dynamic Operation Model for a Class of Closed-loop Logistic System

open access: yes, 2010
The operation process for a class of closed-loop logistic system is considered. This system contains multiple suppliers, manufactories, distribution centers and customers.
Xu Jiawang   +5 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

CLOSED-LOOP CONTROL SYSTEM FOR METAL POWDER LASER SHAPING PROCESS

open access: yes, 2006
The Metal Powder Laser Shaping (MPLS) technology is a new manufacturing technology based on the theory of Rapid Prototyping. MPLS process is affected by multiple factors, such as the power of the laser, the scanning speed of the laser, the feeding rate ...
Xing F(邢飞)   +2 more
core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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