Results 141 to 150 of about 11,569,868 (302)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Acute Isolated Volar Distal Radioulnar Joint Dislocation Treated With Closed Reduction and Percutaneous Kirschner Wire Fixation: A Case Report. [PDF]

Cureus
De Freitas Tobias Y, Figueiredo Bordini A, Cardoso Moraes JV, Rodrigues Pacheco JP.   +3 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Robot-assisted closed reduction and navigated fixation for pelvic ring injuries: a focused narrative review of a reduction-fixation-audit framework. [PDF]

Front Med (Lausanne)
Wu E, Gu F, Zhang W, Li X, Liang Y, Liu Z, Liu S, Liang Y.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Skin laceration during closed reduction of distal radius fracture in the elderly: an underappreciated complication. [PDF]

OTA Int
Upreti A, Adhikari H, Adhikari S.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Superior reduction quality without improved outcomes: open versus closed reduction for displaced femoral neck fractures in adults under 60 years. [PDF]

Arch Orthop Trauma Surg
Chi JE, Liu CH, Lo YH, Lai CY, Chen IJ, Yu YH.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Anesthetic Strategies for Closed Reduction of Dislocated Total Hip Arthroplasty: A Scoping Review. [PDF]

Acta Anaesthesiol Scand
Knudsen RL, Bjulf RHF, Bahuet AR, Steensbæk MT, Jellestad AL, Lange KHW, Lundstrøm LH, Nørskov AK.   +7 more
europepmc   +1 more source