Results 51 to 60 of about 11,569,868 (302)
DEFINABILITY OF DERIVATIONS IN THE REDUCTS OF DIFFERENTIALLY CLOSED FIELDS [PDF]
The Journal of Symbolic Logic, 2017 AbstractLet${\cal F}$=(F; +, .,0, 1, D) be a differentially closed field. We consider the question of definability of the derivation D in reducts of${\cal F}$of the form${\cal F}$R= (F; +, .,0, 1,P)PεRwhereRis some collection of definable sets in${\cal F}$. We give examples and nonexamples and establish some criteria for definability of D.
openaire +3 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Closed anterolateral total talar dislocation: a case report and technical notes
, 2014 Yousef A Alrashidi,1 Zubair A Wali,2 Khalid I Khoshhal11Department of Orthopedic Surgery, College of Medicine, Taibah University, 2Department of Orthopedic Surgery, King Fahd Hospital, Almadinah Almunawwarah, Saudi ArabiaBackground: Standard treatment of
Khoshhal KI, Wali ZA, Alrashidi YA
core
On stochastic balancing related model reduction [PDF]
, 2000 We propose a general method based on the balanced stochastic truncation (BST) approach for the model reduction of stable linear systems. The new method relies on a recent general inner-outer factorization result and extends the applicability of the BST ...
A. Varga, Varga, Andras
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Closed reduction of traumatic atlantoaxial rotatory subluxation with type II odontoid fracture
, 2018 Background: Traumatic atlantoaxial rotatory subluxation (TAARS) in adults is rare. We present an uncommon case of traumatic atlantoaxial rotatory subluxation with an associated type II odontoid fracture in a neurologically intact patient and describe a ...
Stephan du Plessis, MD +2 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Closed reduction of a posterior sternoclavicular joint dislocation: A case report
, 2018 Sternoclavicular joint dislocation (SCJD) is a rare injury; there are only two reported cases of SCJD that have occurred during judo practice. We present a case of an 18-year-old male athlete who fell while practicing judo and experienced upper left ...
Mamoru Okubo +2 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source