Results 201 to 210 of about 4,031,702 (245)

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Research progress on the effects of epidural electrical stimulation on lower extremity function in patients with spinal cord injury. [PDF]

Front Med (Lausanne)
Xie F, Bai C, Luan X, Xu J.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Hierarchical geometric deep learning enables scalable analysis of molecular dynamics. [PDF]

J Chem Phys
Pengmei Z, Guo SC, Lorpaiboon C, Dinner AR.   +3 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Oxonium-Embedded Benzo[<i>b</i>]perylene: A Redox-Switchable Closed-Shell π‑Cation, and Its Paramagnetic Charge-Transfer Salt with TCNE^•. [PDF]

ACS Cent Sci
Duan C, Xue Y, Straus DB, Mariscal A, Ratkovec JL, Arulsamy N, Zhao J, Wang M, Reid OG, Wojtas L, Li X, Liu W, Li P.   +12 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Protocol for a multicenter prospective sequential intervention study: the effect of adaptive closed-loop postural training on gait disorders in hemiparetic stroke patients. [PDF]

Front Neurol
Zhou L, Li J, Xu Y, Kang X, Li J, Liang B, Chen B, Guo Q, Zhang X, Wang Z, Huang T, Xu M, Bao Z, Abdul Rahim NA, Hou Y, Yusof HA.   +15 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Focusing scattered light through live tissue with channel-selected wavefront shaping. [PDF]

Biomed Opt Express
Jia C, Shen Y, Wang Z, Luo J, Zhang Z, Qi D, Yao Y, Deng L, Zhang S.   +8 more
europepmc   +1 more source