KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
New low-genus desingularizations of three Clifford tori and related characterizations. [PDF]
Kapouleas N, Wiygul D.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Magnetic graphs for cavity quantum electrodynamics. [PDF]
Yu S, Piao X, Park N.
europepmc +1 more source
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
The impact of core stability training on jump serve speed in male volleyball players. [PDF]
Li X, Wang W, Zhou C, Shao B.
europepmc +1 more source
GCT-BCLN: a bidirectional closed-loop network for nondestructive detection of rice seed vigor using hyperspectral imaging. [PDF]
Yan L +7 more
europepmc +1 more source
Moderated designs can balance between batch-effect mitigation and cell loss due to hashtag-assisted pooling in single-cell experiments. [PDF]
Chatterjee B +8 more
europepmc +1 more source
Deep learning directed synthesis of fluid ferroelectric materials.
Parton-Barr C +8 more
europepmc +1 more source

