Results 61 to 70 of about 1,537 (194)

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

Prenatal Diagnosis to Postnatal Outcomes of Saccular Forms of Closed Spina Dysraphism: A Single Center Retrospective Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To describe prenatal imaging findings and postnatal outcomes in fetuses diagnosed with saccular forms of closed spinal dysraphism (CSD). Methods This retrospective single‐centre study included fetuses diagnosed with non‐genetic, non‐syndromic CSD between January 2018 and June 2023.
Yada Kunpalin, Jennifer Quon, Abby Varghese, Michael Chua, Samer Maher, Abhaya V. Kulkarni, Tim Van Mieghem, Shiri Shinar, Elka Miller   +8 more
wiley   +1 more source

Parental counselling and autopsy results: A retrospective diagnostic cohort study at a multidisciplinary fetal neurology clinic

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70022 Abstract Aim To examine the accuracy of prenatal counselling at a multidisciplinary fetal neurology clinic (FNC) that led to termination of pregnancy (TOP), to improve the quality of future consultations. Method This retrospective diagnostic cohort study compared the imaging
Avi Shariv, Michal Gafner, Zvi Leibovitz, Letizia Schreiber, Dvora Kidron, Ayala Arad, Efrat Hadi, Stephanie Libzon, Liat Ben Sira, Maya Goldschmidt Manor, Dorit Lev, Tally Lerman‐Sagie, Liat Gindes   +12 more
wiley   +1 more source

Prenatal Diagnosis of Congenital Dermal Sinus [PDF]

, 2015
Background Congenital dermal sinus (CDS) is an uncommon form of spinal dysraphism. Although postdelivery identification in the neonate is aided by several associated physical examination findings, establishing this diagnosis prenatally has proven to be ...
Gonik, Bernard, Malik, Asif, Malik, Ghaus, Mohan, Yedathore, Sakr, Sharif   +4 more
core   +6 more sources

Neonatal Arnold–Chiari II Malformation: An Imaging‐Focused Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Arnold‐Chiari Malformation Type II (CM‐II) is a serious congenital hindbrain disorder marked by the displacement of the cerebellum and brainstem downwards through the foramen magnum. CM‐II is frequently linked with myelomeningocele and hydrocephalus.
Mohammad Alashqar, Seba Lubbadeh, Ahmed Daraghrmah, Ahmad Alashqar, Zaina Khaled, Suleiman Sbeih, Amjad Bdair, Israa Salman, Mohammed I. Abu Kamesh   +8 more
wiley   +1 more source

Pattern of Presentation of Spinal Dysraphism [PDF]

, 2022
Objective:  To assess the pattern of presentation of spinal dysraphism and compare with already available data on the subject. Design:  Prospective study. Material and Method:  This prospective study was done in the department of
MUBASHER AHMED, SAJID HUSSAIN MUGHAL
core   +1 more source

Factors Affecting the Quality of Life of Parents of Children With Spina Bifida: The Mediating Role of Family Resilience

Journal of Advanced Nursing, Volume 82, Issue 2, Page 1371-1381, February 2026.
ABSTRACT Aims To investigate factors affecting the quality of life of parents of children with spina bifida and examine how family resilience mediates between parental depression and quality of life. Design Cross–sectional study. Methods Secondary data analysis was performed using first‐year data from a five‐year spina bifida cohort project (2022–2026)
Kyua Kim, Hyeseon Yun, Hooyun Lee, Kijun Song, Marcia Van Riper, Eun Kyoung Choi   +5 more
wiley   +1 more source

Introduction of a urodynamic score to detect pre- and postoperative neurological deficits in children with a primary tethered cord [PDF]

, 2018
Object: An increasing number of asymptomatic children are diagnosed with occult spinal dysraphism, raising the question of their optimal management. Urodynamic study (UDS) is the most reliable method of detecting neuro-urological abnormalities in these ...
Forcada-Guex, Margarita, Lutz, Nicolas, Meyrat, Blaise, Rilliet, Bénédict, Tercier, Stéphan, Vernet, Olivier   +5 more
core  

Congenital anomalies of the vertebrae in dogs [PDF]

, 2017
In this review article, a overview is given of the congenital pathologies of vertebrae in the dog. These pathologies are common in dogs and can be divided in two major groups: neural tube defects or spinal dysraphism, such as spina bifida with or without
De Rycke, Lieve, Saunders, Jimmy
core   +1 more source

Validation of QUALAS-T, a health-related quality of life instrument for teenagers with spina bifida [PDF]

, 2017
Introduction We aimed to develop and validate a self-reported QUAlity of Life Assessment in Spina bifida for Teenagers (QUALAS-T). Material and methods We drafted a 46-question pilot instrument using a patient-centered comprehensive item generation ...
Cain, Mark P., Casey, Jessica T., Kaefer, Martin, King, Shelly J., Misseri, Rosalia, Raposo, Sonia-Maria, Rink, Richard C., Szymański, Konrad M., Whittam, Benjamin, Yang, David Y.   +9 more
core   +1 more source