By integrating taxonomic and functional profiling of 1543 adult gut metagenomes, this study identified microbial taxa and enzymatic functions associated with increasing Body Mass Index. Function‐centered taxonomic back‐tracing of branched‐chain amino acid transaminase, nucleotide diphosphatase, and phosphatidylserine decarboxylase revealed only limited
Silvia Petraro +6 more
wiley +1 more source
Microbiome Responses of Beef Steers to Rotational Grazing of Toxic Endophyte-Infected Tall Fescue Under Fall Conditions. [PDF]
Llada IM +8 more
europepmc +1 more source
Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang +7 more
wiley +1 more source
Defined human Clostridia consortia reverse colitis via dual effects of tryptophan metabolites on microbiota and immunity. [PDF]
Oka A +20 more
europepmc +1 more source
Compared with the two herbivorous comparison species, pandas showed higher estimated oral‐source contributions and enrichment of microbial traits associated with facultative anaerobiosis, biofilm formation, and stress tolerance. These patterns are consistent with a model in which greater oral microbial input and putative host filtering may jointly ...
Lu Huang +7 more
wiley +1 more source
Clinical Features of Clostridial Necrotizing Soft-tissue Infections: Analysis of a Prospective Scandinavian Cohort Study. [PDF]
Viste JA +8 more
europepmc +1 more source
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Evaluation of the jejunal microbiota and microbial markers in laying hens fed diets with black soldier fly larval fat as a partial or total replacement for soybean oil. [PDF]
Kierończyk B +9 more
europepmc +1 more source
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang +9 more
wiley +1 more source
A genomic atlas of gut clostridia: phylogeny, butyrate, and propionate production. [PDF]
Sola L +5 more
europepmc +1 more source

