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Factors driving increases in Clostridioides difficile infection rates in England: A national case-control study, 2019 to 2024

Whiteley T, Charlett A, Chudasama D, Amin-Chowdhury Z, Hope R, Fellowes L, Jeyaratnam D, Oettle R, Robotham J, Stevens C, Stimson J, Inns T, Evans S.   +12 more
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Clostridioides difficile

Journal of Pediatric Surgical Nursing, 2022
Abstract The purpose of this article is to present an exemplar related to diagnostic testing whereby reasoned decisions can assist the pediatric surgical clinician in the expeditious screening, diagnosis, and management of Clostridioides difficile infection (CDI). In 2017, the Emerging Infections Program for CDI reported that the incidence of
Eliane de Oliveira Ferreira, Gerly Anne de Castro Brito   +1 more
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The future of Clostridioides difficile diagnostics

Current Opinion in Infectious Diseases, 2021
Purpose of review Although the epidemiology of Clostridioides difficile has changed, this organism continues to cause significant morbidity and mortality. This review addresses current and future approaches to the diagnosis of C. difficile disease.
Masako, Mizusawa, Karen C, Carroll
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Clostridioides difficile colitis

2021
Clostridioides difficile (C. diff) is the most frequently reported nosocomial pathogen and a leading cause of morbidity and mortality in hospitalized patients. In the USA 435,000 infections are annually reported, with 29,000 deaths. C. diff infection quadruples hospitalization costs.
openaire   +1 more source

Antimicrobial resistance in Clostridioides difficile

European Journal of Clinical Microbiology & Infectious Diseases, 2021
Antimicrobial resistance (AMR) in Clostridioides difficile remains a significant threat to global healthcare systems, not just for the treatment of C. difficile infection (CDI), but as a reservoir of AMR genes that could be potentially transferred to other pathogens. The mechanisms of resistance for several antimicrobials such as metronidazole and MLSB-
O'Grady, K., Knight, D.R., Riley, T.V.
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Clostridioides difficile Colitis

Surgical Clinics of North America
Clostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile
Luke, Pumiglia, Lexi, Wilson, Laila, Rashidi   +2 more
openaire   +2 more sources