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The future of Clostridioides difficile diagnostics
Current Opinion in Infectious Diseases, 2021Purpose of review Although the epidemiology of Clostridioides difficile has changed, this organism continues to cause significant morbidity and mortality. This review addresses current and future approaches to the diagnosis of C. difficile disease.
Karen C. Carroll, Masako Mizusawa
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Antimicrobial resistance in Clostridioides difficile
European Journal of Clinical Microbiology & Infectious Diseases, 2021Antimicrobial resistance (AMR) in Clostridioides difficile remains a significant threat to global healthcare systems, not just for the treatment of C. difficile infection (CDI), but as a reservoir of AMR genes that could be potentially transferred to other pathogens. The mechanisms of resistance for several antimicrobials such as metronidazole and MLSB-
Keeley O’Grady +3 more
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Clostridioides difficile colitis
2021Clostridioides difficile (C. diff) is the most frequently reported nosocomial pathogen and a leading cause of morbidity and mortality in hospitalized patients. In the USA 435,000 infections are annually reported, with 29,000 deaths. C. diff infection quadruples hospitalization costs.
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Clostridioides difficile in bat guano
Comparative Immunology, Microbiology and Infectious Diseases, 2019Bats are associated with the emergence of several mammalian diseases. Their sessional migration, and tendency to form large colonies in close proximity to human habitats enables effective intra- and inter-species transmission of pathogens. Clostridioides difficile is an important enteric pathogen in humans and animals; however, the source of its ...
Petra Bandelj +6 more
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Clostridioides difficile Colitis
Surgical Clinics of North AmericaClostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile
Luke, Pumiglia +2 more
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Clostridioides difficile Colitis
2020A 32-year-old woman presents with 3 days of crampy abdominal pain associated with frequent loose stools. She states that the diarrhea is now bloody and is occurring almost every hour. She was in good health until 2 weeks ago when she was diagnosed with pyelonephritis, treated with a 10-day course of ciprofloxacin.
Joseph B. Domachowske +1 more
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