Results 231 to 240 of about 44,840 (262)

Emerging alternatives against Clostridioides difficile infection

Anaerobe, 2022
Clostridioides difficile infection (CDI) is a significant worry within healthcare institutions and the community. It is one of the leading agents causing severe diarrhea worldwide. Effective management is critical since the morbidity and mortality attributed to CDI have increased exponentially over the past 20 years.
Romero-Rodriguez, A., Martinez de la Pena, C., Troncoso-Cotal, S., Guzman, C., Sanchez, S.   +4 more
openaire   +3 more sources

Clostridioides difficile infections among healthcare workers

American Journal of Infection Control, 2020
Health care workers (HCWs) are constantly exposed to patients with Clostridiodes difficile infection (CDI) although their risk developing infection is unknown. We designed a retrospective comparative study including HCWs with CDI and 2 comparator groups with a 1:2 ratio: HCWs without CDI and admitted patients with CDI.
Gloria M. Aguirre-García, Elvira Garza-González, Rayo Morfin-Otero, Adrián Camacho-Ortiz   +3 more
openaire   +2 more sources

[Clostridioides difficile infections].

Nederlands tijdschrift voor geneeskunde, 2023
Here, we describe the epidemiology, diagnostics, and treatment of Clostridioides difficile infection (CDI) in the primary health care setting. CDI is traditionally considered as a healthcare associated infection. However, infections with onset in the community represent a large proportion of CDI.
Joffrey, van Prehn, Vlada O, Chernova, Karuna E W, Vendrik, Ed J, Kuijper   +3 more
openaire   +1 more source

Clostridioides difficile-Infection (CDI)

VacciTUTOR, 2022
Clostridioides difficile is a Gram positive, spore-forming bacillus colonizing the lower gastrointestinal tract. Use of antibiotics, older age, and underlying diseases contribute to changes in the microbial flora of the gut, which may lead to the production of toxins that cause C.
openaire   +1 more source

Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

Clinical Microbiology Reviews
SUMMARY Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections. This bacterium is constantly evolving and poses complex challenges for clinicians, often encountered in real-life scenarios.
Stefano Di Bella, Gianfranco Sanson, J. Monticelli, V. Zerbato, Luigi Principe, Mauro Giuffrè, G. Pipitone, R. Luzzati   +7 more
semanticscholar   +1 more source

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Science
Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine targeting C. difficile toxins and virulence factors.
M. Alameh, Alexa Semon, Nile U Bayard, Yi-Gen Pan, Garima Dwivedi, James J. Knox, Rochelle C. Glover, Paula C. Rangel, Ceylan Tanes, K. Bittinger, Qianxuan She, Haitao Hu, Srinivisa Reddy Bonam, Jeffrey R. Maslanka, P. Planet, Ahmed M. Moustafa, Benjamin Davis, A. Chevrier, Mitchell Beattie, Houping Ni, Gabrielle S Blizard, Emma E Furth, R. Mach, M. Lavertu, Mark A. Sellmyer, Ying K Tam, Michael C. Abt, D. Weissman, J. P. Zackular   +28 more
semanticscholar   +1 more source

Clostridioides difficile infection diagnosis

Annales de Biologie Clinique
Clostridioides difficile is a Gram-positive, spore-forming anaerobic enteropathogen responsible for a wide spectrum of clinical diseases ranging from mild diarrhoea to pseudomembranous colitis. It is the first cause of healthcare-associated diarrhoeas, but community-associated Clostridioides difficile infections (CDI) are increasingly reported in ...
Jeanne, Couturier, Muriel, Ehmig, Imane, Mostaghat, Frédéric, Barbut   +3 more
openaire   +2 more sources