Results 151 to 160 of about 220,541 (313)

Targeting the Tumor Microbiota in Cancer Therapy Basing on Nanomaterials

open access: yesExploration, EarlyView.
Intra‐tumoral microbiota, which is a potential component of the tumor microenvironment, has been emerging as a key participant and driving factor in cancer. This article reviews the latest progress in this field, including the microbial community within tumors and its pro‐cancer mechanisms, as well as the anti‐tumor strategies targeting intra‐tumoral ...
Yanan Niu   +4 more
wiley   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

open access: yesExploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang   +6 more
wiley   +1 more source

GERMINATION OF CLOSTRIDIUM SPORES IN BUFFERED GLUCOSE [PDF]

open access: bronze, 1954
E. Staten Wynne   +2 more
openalex   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Deciphering the Potential Causal and Prognostic Relationships Between Gut Microbiota and Brain Tumors: Insights from Genetics Analysis and Machine Learning

open access: yesExploration, EarlyView.
The causal relationship between gut microbiota and brain tumors and potential prognostic value of microbiota are still unclear. This study confirmed the causal effects of specific gut microbiota on three common brain tumors and identified microbe‐related genes that are expressed in brain tissue and correlated with the abundance of gut microbiota ...
Changwu Wu   +7 more
wiley   +1 more source

Highland Barley‐Derived Polyphenols: A Category of Bioactive Phytochemicals Beneficial for Intestinal Health

open access: yesFood Chemistry International, EarlyView.
This minireview highlights that highland barley polyphenols (HBPPs) regulate gut microbiota and promote intestinal homeostasis through antioxidant/anti‐inflammatory activities, barrier reinforcement, and immune modulation, mediated by interactions among HBBPs, intestinal microbiota and intestinal cells.
Yi‐Peng Bai   +2 more
wiley   +1 more source

Effect of the Synthetic Bile Salt Analog CamSA on the Hamster Model of Clostridium difficile Infection

open access: yes, 2018
Clostridium difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea and has gained worldwide notoriety due to emerging hypervirulent strains and the high incidence of recurrence. We previously reported protection of mice from CDI
Abel-Santos, Ernesto   +9 more
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