Results 261 to 270 of about 220,541 (313)

Comparison of the effects of occlusal splint and Botox injections on the amount of mouth opening and chronic pain in individuals with temporomandibular disorders: a systematic review and meta‐analysis

open access: yesAustralian Dental Journal, EarlyView.
Abstract Objective This systematic review and meta‐analysis study was carried out to compare the effectiveness of occlusal splint (OS) and Botox (BTX) injections in temporomandibular disorders (TMDs). Material and Methods Irrespective of the starting year, studies were searched for up to 2024 using PubMed, Web of Science, Scopus databases and the ...
Ö İşisağ, H Atasoy, S Yıldız
wiley   +1 more source

The Optimal Timing and Duration of Daily G‐CSF for the Primary Prevention of Febrile Neutropenia in Breast Cancer Patients Undergoing Adjuvant TAC Chemotherapy

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
The study aimed to determine the optimal timing and duration of filgrastim administration for the primary prevention of febrile neutropenia (FN) in breast cancer patients undergoing adjuvant TAC chemotherapy. Our findings suggest that initiating daily filgrastim from Day 2 and continuing for 7 days optimizes toxicity reduction.
Zisun Kim   +7 more
wiley   +1 more source

Integrated Efficacy and Safety Analysis of Abrocitinib in Adolescents With Moderate‐to‐Severe Atopic Dermatitis

open access: yesAllergy, EarlyView.
Data were included from adolescents with moderate‐to‐severe AD treated with the JAK1 inhibitor abrocitinib (200 mg/100 mg) across JADE clinical trials. Improvements in skin clearance (per EASI‐75) and itch (per PP‐NRS4) were maintained for up to 112 weeks with both abrocitinib doses.
Amy S. Paller   +13 more
wiley   +1 more source

Direct Single‐Dose Drug‐Provocation Test Is Safe for Delabelling Penicillin Low‐Risk Reactions in Adults

open access: yesAllergy, EarlyView.
We show that direct single‐dose provocation test was both safe and effective in delabeling penicillin allergy in low‐risk adult patients, including those with mild delayed skin reactions and those with unknown reactions, such as childhood labels and past syncope episodes. In those who react in the drug provocation test, a T‐cell mechanism was confirmed
Marina Labella   +7 more
wiley   +1 more source

Peyronie's disease in the United States: A real‐world, 13‐year nationwide analysis of demographics, clinical characteristics, and treatment trends

open access: yesAndrology, EarlyView.
Abstract Background Real‐world data on Peyronie's disease remains limited. Objectives Describe the demographics, clinical characteristics, and therapeutic management of Peyronie's disease patients in the United States. Materials and methods A retrospective analysis was conducted using the PearlDiver Mariner database (2010–2022).
Angelo Orsini   +15 more
wiley   +1 more source

Enterocolitis associated with glofitamab—First report and clinicopathological findings in three cases

open access: yesBritish Journal of Haematology, EarlyView.
Summary Glofitamab is a CD3‐CD20 bispecific antibody used to treat B‐cell non‐Hodgkin lymphoma. We describe three cases of enterocolitis occurring with glofitamab at a single institution. Similarities between cases include onset post cycle 4–5, moderately elevated faecal calprotectin, abnormal bowel avidity on positron emission tomography scan (2/3 ...
Sean McKeague   +8 more
wiley   +1 more source

Experimental Parkinsonism induced by tetanus toxin injected into basal ganglia

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Local inhibitory circuits and long‐range inhibitory projections within the interconnected basal ganglia nuclei are critical for control of voluntary movement and pathophysiology of different extrapyramidal movement disorders.
Patrik Meglić   +6 more
wiley   +1 more source

Early Origins of Asthma and Allergies: Clues From Studies in China

open access: yesClinical &Experimental Allergy, EarlyView.
The environment we live in harbours both risk and protective factors for asthma and allergies. This is particularly relevant in China, where unique environmental and cultural factors shape disease development. The interplay between these environmental factors, airway immunity, and gut microbiome shapes the susceptibility to asthma and allergies ...
Yike Wang   +5 more
wiley   +1 more source

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