Results 131 to 140 of about 110,558 (326)

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]

, 2018
Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch, Abt, Ananthakrishnan, Barbour, Bartolotta, Bergsson, Bhattacharjee, Buckley, Burke, Carpo, Chen, Clark, Croasdell, Crowther, Dapa, Dapa, Dayrit, de Roos, Deakin, Deng, Desai, Edwards, Ekanayaka, Eyres, Ferreyra, Fischer, Francis, Galbraith, German, Harnvoravongchai, Hinton, Huang, Hung, Hung, Immanuel, Johnson, Kabara, Katan, Kim, Kint, Kitahara, Kliewer, Liu, Louie, Lynch, Martin, Martin, May, McDonald, McEllistrem, Miller, Nakatsuji, Namkung, Nobmann, Pettit, Pizarro-Guajardo, Pruitt, Rodriguez-Palacios, Rouse, Ruhr, Ruzin, Shearer, Shilling, Smits, Sorg, Surawicz, Theinsathid, Thompson, Vardakas, Villafuerte Galvez, Wilcox, Yonezawa   +71 more
core   +1 more source

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases

Neuroprotection, EarlyView.
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide, Omamuyovwi M. Ijomone   +1 more
wiley   +1 more source

Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

BMC Pharmacology and Toxicology, 2017
Background Surotomycin, a novel, orally administered, cyclic, lipopeptide antibacterial in development for the treatment of Clostridium difficile-associated diarrhea, has demonstrated minimal intestinal absorption in animal models.
Gurudatt Chandorkar, Qiao Zhan, Julie Donovan, Shruta Rege, Hernando Patino   +4 more
doaj   +1 more source

Synergistic efficacy of 405 nm light and chlorinated disinfectants for the enhanced decontamination of Clostridium difficile spores [PDF]

, 2016
The ability of Clostridium difficile to form highly resilient spores which can survive in the environment for prolonged periods causes major contamination problems.
Anderson, John G., Coia, John E., MacGregor, Scott J., Maclean, Michelle, Moorhead, Sian   +4 more
core   +1 more source

Removing bias due to finite measurement of dynamic systems: case study on P2P systems [PDF]

13es Rencontres Francophones sur les Aspects Algorithmiques de T\'el\'ecommunications (AlgoTel) (2011), 2011
Mesurer avec pr\'ecision la dynamique des graphes de terrain est une t\^ache difficile, car les propri\'et\'es observ\'ees peuvent \^etre biais\'ees pour diff\'erentes raisons, en particulier le fait que la p\'eriode de mesure soit finie. Dans ce papier, nous introduisons une m\'ethodologie g\'en\'erale qui nous permet de savoir si la fen\^etre d ...
arxiv  

Efficacy of microbial cell‐free DNA testing for detecting pathogens in pediatric patients with head and neck infections—An initial study

Pediatric Investigation, EarlyView.
We investigate the utility of microbial cell‐free DNA (mcfDNA) from the blood to predict surgical culture results. In this study, only 26.9% of patients had mcfDNA results that were considered predictive of the causative organism(s). There was a significant burden of contamination in the cohort, emphasizing that dedicated protocols must be followed ...
Audrey Xu, Andrea Miranda, Hung Fu Lin, Taseer Din, Karthik Balakrishnan, Mai Thy Truong, Iram Ahmad, Kara Meister   +7 more
wiley   +1 more source

Multifocal Clinical Performance Improvement across 21 Hospitals

Journal for Healthcare Quality, EarlyView., 2013
Abstract Improving quality and safety across an entire healthcare system in multiple clinical areas within a short time frame is challenging. We describe our experience with improving inpatient quality and safety at Kaiser Permanente Northern California.
Barbara Crawford, Melinda Skeath, Alan Whippy   +2 more
wiley   +1 more source

The Issue of Early Diagnosis of Intestinal Complications at Antibiotic Therapy in Children

Zdorovʹe Rebenka, 2015
The objective of the research was to improve the timely diagnosis of intestinal complications of antibiotic therapy, caused by Clostridium difficile infection in children.
O.A. Radutna, O.H. Ivanko, N.V. Kyzyma, O.S. Krut   +3 more
doaj   +1 more source

Effects of Clostridium difficile on the human immune response [PDF]

, 2013
Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics.
McGovern, Mike
core   +1 more source

Glycoproteomics and Its Role in Understanding Bacterial O‐Linked Glycosylation

PROTEOMICS, EarlyView.
ABSTRACT Protein glycosylation is now recognized as a ubiquitous process observed in all domains of life. Within bacterial species, carbohydrates can be attached to multiple residues with glycosylation of serine, threonine, or tyrosine residues via their hydroxyl side chains referred to as O‐linked glycosylation.
Kristian I. Karlic, Hamza Tahir, Nichollas E. Scott   +2 more
wiley   +1 more source