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2018
Clostridium difficile infection (CDI) is an important healthcare-associated disease worldwide, mainly occurring after antimicrobial therapy. Antibiotics administered to treat a number of infections can promote C. difficile colonization of the gastrointestinal tract and, thus, CDI.
Claudia, Vuotto +3 more
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Clostridium difficile infection (CDI) is an important healthcare-associated disease worldwide, mainly occurring after antimicrobial therapy. Antibiotics administered to treat a number of infections can promote C. difficile colonization of the gastrointestinal tract and, thus, CDI.
Claudia, Vuotto +3 more
openaire +2 more sources
Clinical Infectious Diseases, 2019
Clostridium difficile is a significant pathogen in healthcare today, impacting both hospitalized and community-based patients. Immunocompromised patients experience a high incidence of C.
S. Revolinski, L. Munoz-Price
semanticscholar +1 more source
Clostridium difficile is a significant pathogen in healthcare today, impacting both hospitalized and community-based patients. Immunocompromised patients experience a high incidence of C.
S. Revolinski, L. Munoz-Price
semanticscholar +1 more source
Clostridium difficile infection
The Lancet, 2008Clostridium difficile is a Gram-positive, anaerobic, spore-producing anaerobe [1] responsible for approximately 50–70% of gastrointestinal infections in hospitalized patients [2, 3]. An episode of C. difficile infection (CDI) is defined as a clinical picture compatible with CDI (i.
Kuipers, Ernst, Surawicz, CM
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Clostridium difficile Infection
Infectious Disease Clinics of North America, 2017Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and ...
Luis, Alcalá Hernández +2 more
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Community Clostridium difficile
BMJ, 2009We reviewed clinical and microbiology data on patients with positive results for C difficile toxin in this NHS trust from May 2007 to April 2008.1 General practitioners’ practice in requesting tests for C difficile toxin varied widely. …
Jayakeerthi, Rangaiah +2 more
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Clostridium difficile Adhesins
2016Clostridium difficile is responsible for a large spectrum of intestinal diseases ranging from mild diarrhea to fatal colitis depending on the one hand on the strain virulence and on the other on the host. The pathogenesis of C. difficile infection could be seen as a three-step process that takes place after disruption of the digestive microbiota by ...
Séverine, Péchiné +2 more
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Surgical Clinics of North America, 2009
Clostridium difficile is the most common cause of infectious diarrhea in hospitalized patients. Its effects are mediated by C difficile toxins A and B. Recent outbreaks of severe colitis have been associated with a new strain of the bacterium that produces large amounts of the toxins. Although oral metronidazole and oral vancomycin can be used to treat
Philip A, Efron, John E, Mazuski
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Clostridium difficile is the most common cause of infectious diarrhea in hospitalized patients. Its effects are mediated by C difficile toxins A and B. Recent outbreaks of severe colitis have been associated with a new strain of the bacterium that produces large amounts of the toxins. Although oral metronidazole and oral vancomycin can be used to treat
Philip A, Efron, John E, Mazuski
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Update on Clostridium difficile
Current Treatment Options in Gastroenterology, 2006The most dramatic change in the past several years has been the increased incidence and severity of Clostridium difficile colitis reported from multiple countries. A number of factors have likely contributed to this. One major event has been the emergence of a fluoroquinolone-resistant clone of C.
Cheleste M, Thorpe, Sherwood L, Gorbach
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Clostridium difficile Infection
Critical Reviews in Clinical Laboratory Sciences, 1996The spore-forming anaerobe Clostridium difficile has become a serious enteropathogen. Changes in the composition of natural intestinal flora, mainly due to antibiotic therapy, permit its colonization of, and multiplication in, the colon. The disease is caused by (entero)toxin A and (cyto)toxin B, and infection ranges from asymptomatic carrier state and
Dieter H. M. Gröschel, B. Toye
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