Results 61 to 70 of about 75,986 (146)
PD‐L1‐Binding Antigen Presenters: Redirecting Vaccine‐Induced Antibodies for Cancer Immunotherapy
The PBAP‐gE complex anchors gE antigen to PD‐L1 on tumor cells. Vaccine‐induced anti‐gE antibodies simultaneously engage FcγRIIIa on NK cells and tumor‐bound PBAP‐gE, triggering NK cell activation and antibody‐dependent cellular cytotoxicity, thereby selectively eliminating PD‐L1–expressing tumor cells.
Huixin Gao +24 more
wiley +1 more source
Vaccine Production to Protect Animals Against Pathogenic Clostridia
Clostridium is a broad genus of anaerobic, spore-forming, rod-shaped, Gram-positive bacteria that can be found in different environments all around the world.
Nicolas E. Zaragoza +4 more
doaj +1 more source
ABSTRACT Background and Aims Understanding the predictors of Tetanus Toxoid (TT) protection among women of reproductive age is essential for designing effective interventions to eliminate Maternal and Neonatal Tetanus (MNT) in Somaliland. This study aims to identify the sociodemographic, economic, and geographic determinants of TT protection. Methods A
Mustafe Maxamed Cabdi +7 more
wiley +1 more source
El tétanos es una grave y frecuentemente letal infección anaeróbica producida por la neurotoxina del Clostridium tetani, microorganismo que prolifera en tejidos hipóxicos, desvitalizados y altamente contaminados con tierra y excrementos.
José Félix Patiño
doaj
Evaluating Dog Bite‐Induced Facial Trauma: A Study From a Single Tertiary Care Center
Abstract Objective Analyze demographic and clinical factors for patients presenting with dog bites to the face, head, or neck. Study Design Retrospective cohort. Setting Single tertiary care, level 1 trauma center. Methods A retrospective chart review identified patients presenting for facial dog bite injuries from 2012 to 2023.
Andrew J. Rothka +5 more
wiley +1 more source
Tétano em bovinos no sul do Rio Grande do Sul: estudo de 24 surtos
São descritos vinte e quatro surtos de tétano ocorridos no ano 2009 em bovinos de corte em propriedades situadas na região de influência do Laboratório Regional de Diagnóstico (LRD), sul do Rio Grande de Sul.
Pedro S. Quevedo +7 more
doaj +1 more source
Case Summary A 3‐month‐old Airedale dog with clinically diagnosed generalized tetanus was investigated for the occurrence of excessive paddling and chewing movements when sleeping.
Marguerite Knipe +2 more
doaj +1 more source
ABSTRACT Background and Aims Tetanus, caused by Clostridium tetani, results in rigor spasms and remains as major cause of mortality in areas with poor vaccination and sanitation. Mortality has been cited to be 20%–55% in Ethiopia, possibly due to variation in healthcare, immunization, and intensive care access.
Mulugeta Tesfaw +3 more
wiley +1 more source
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
Immunotherapeutic Applications of Probiotics in Infectious Diseases Management: A Scoping Review
Probiotics are emerging as promising alternative therapies with diverse health applications, particularly in enhancing immunity and combating infectious diseases. This scoping review synthesizes evidence on the immunomodulatory and antimicrobial effects of well‐characterized strains, particularly species of Bifidobacterium and Lactobacillus. Probiotics
Samson Adedeji Adejumo +8 more
wiley +1 more source

