Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Anatomic rupture location, leukocyte levels and diabetes mellitus as factors influencing in-hospital mortality following percutaneous repair of post-infarction ventricular septal rupture: a single centre study. [PDF]
Habib F +3 more
europepmc +1 more source
CLOSURE OF DEFECTS OF LIPS WITH COMPOSITE VERMILION BORDER-LINED FLAPS
Hans May
openalex +2 more sources
Closure to “Discussion of ‘Design Aspects of High-Temperature Fatigue With Particular Reference to Thermal Stresses’” (1956, Trans. ASME, 78, p. 532) [PDF]
L. F. Coffin
openalex +1 more source
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Sealing the Gap: Innovative Use of Fibrin Sealant in the Zenker Peroral Endoscopic Myotomy Complication Management. [PDF]
Alkomos MF, Baddoura W, Cavanagh Y.
europepmc +1 more source
Closure to “Discussion of ‘A Three-Dimensional, Tool-Life Equation—Machining Economics’” (1959, ASME J. Eng. Ind., 81, p. 249) [PDF]
Bertil N. Colding
openalex +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Optimizing Primary Closure of Anterolateral Thigh Flap Donor Sites Through Literature Review and Clinical Analysis. [PDF]
Chen CE +7 more
europepmc +1 more source
Closure to “Stilling Basin Experiences of the Corps of Engineers” [PDF]
R. H. Berryhill
openalex +1 more source

