Results 251 to 260 of about 957,959 (360)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation. [PDF]

Transl Pediatr
Mwizerwa L, Joye R, Cousin VL, Malaspinas I, Bouhabib M, Lucron H, Beghetti M, Wacker J.   +7 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Immediate versus delayed closure of facial dog-bite wounds: Retrospective analysis and nursing care experience. [PDF]

Medicine (Baltimore)
Dang Y, Zhao X, Pan T, Wu Y, Jiang X, Hu Y, Huang T, Liu P, Li B, Chen Z, Zhang Y.   +10 more
europepmc   +1 more source

A meaningful closure [PDF]

Intensive Care Medicine, 2014
openaire   +3 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Polyglycolic Acid Sheet Application to Refractory Delayed Bleeding After Rectal Endoscopic Submucosal Dissection: A Case Report. [PDF]

DEN Open
Nakano Y, Kuriyama K, Watanabe Y, Miyamoto S.   +3 more
europepmc   +1 more source

Closure of Colostomies [PDF]

Postgraduate Medical Journal, 1945
openaire   +3 more sources

Middle Miocene closure of the Central American Seaway

Science, 2015
C. Montes, A. Cardona, C. Jaramillo, A. Pardo, J. Silva, V. Valencia, C. Ayala, L. Pérez‐Angel, L. Rodriguez-Parra, V. Ramirez, H. Niño   +10 more
semanticscholar   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source