Results 121 to 130 of about 19,426 (215)

High‐Resolution Genomic Characterization of WAGR Spectrum Disorder: Insights From a Novel Cohort and Literature Synthesis, and Validation of Patient‐Reported Data

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 9, Page 1989-1999, September 2026.
ABSTRACT WAGR spectrum disorder (WAGRSD) is an ultra‐rare congenital disorder caused by heterozygous deletion of chromosome 11p13. While classically associated with Wilms tumor, Aniridia, Genitourinary anomalies, and a Range of developmental delays, accurate delineation of the deletion is critical for prognosis because the phenotypic spectrum extends ...
Andrew M. George   +11 more
wiley   +1 more source

Clinical modifiers of the association between type 1 diabetes and dementia incidence

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Type 1 diabetes mellitus (T1DM) increases dementia risk. Understanding clinical modifiers of that effect could inform prevention. METHODS We analyzed data from All of Us. Participants were aged ≥50 years with T1DM (n = 5,442) or no diabetes (n = 226,819).
Anna M. Pederson   +13 more
wiley   +1 more source

Bilateral Simultaneous Acute Angle-Closure Glaucoma Following Over-the-Counter Cold Medication. [PDF]

open access: yesCase Rep Ophthalmol Med
Vivarelli C   +6 more
europepmc   +1 more source

Distinct ocular microvascular alterations in Alzheimer's disease and cerebral small vessel disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION While both Alzheimer's disease (AD) and cerebral small vessel disease (CSVD) involve vascular dysfunction, the ocular microvascular differences between them remain largely underinvestigated. METHODS This cross‐sectional study included 650 participants (149 AD, 276 CSVD, and 225 cognitively unimpaired individuals).
Ziyi Zhang   +15 more
wiley   +1 more source

MCH‐Guard: Multimodal machine learning framework for risk stratification of cerebral microhemorrhage risk in the Alzheimer's Disease Neuroimaging Initiative

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Efficient cerebral microhemorrhage (MCH) monitoring is critical for anti‐amyloid therapy safety due to amyloid‐related imaging abnormalities with hemosiderin deposition (ARIA‐H) risk. We developed MCH‐Guard, a multimodal machine‐learning framework, to stratify MCH risk for Alzheimer's Disease Neuroimaging Initiaitive (ADNI ...
Alper Gel   +5 more
wiley   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3037-3048, September 2026.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin   +7 more
wiley   +1 more source

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