Results 211 to 220 of about 21,128 (300)

Crosstalk between endoplasmic reticulum stress and mitochondrial homeostasis: A new perspective on ophthalmic disease treatment

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang, Gongsang Cuomu, Sang Jijia, Yumei Yang, Jufen Liu, Yumin Tao   +5 more
wiley   +1 more source

GWAS for primary angle-closure glaucoma identifies loci related to ocular biometry and morphology. [PDF]

Nat Commun
Luben RN, Biradar MI, Stuart KV, Hu R, Sun Z, Li Z, Wang N, Do T, Pang CP, Nakano M, Tashiro K, Ikeda Y, Tokuda Y, Tanaka M, Omi N, Ueno M, Sotozono C, Kinoshita S, Mori K, Kitnarong N, Fea A, Melo MB, Vasconcellos JPC, Costa VP, Nongpiur ME, Ho CL, Perera SA, Craig JE, Kolovos A, Liza-Sharmini AT, Leuenberger EU, Park KH, Vijaya L, George R, Aung T, Khor CC, Foster PJ, Hysi P, Khawaja AP.   +38 more
europepmc   +1 more source

Nanoparticles in Vascular Dementia: Advantages and Challenges

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review highlights the dual diagnostic and therapeutic potential of nanomaterials in Vascular Dementia (VaD). By effectively crossing the blood–brain barrier, functionalized nanoparticles facilitate early diagnosis by targeting Aβ deposits and vascular lesions.
Xianxin Liu, JiaLi Hu, Yueming qiu, Huaying Wang, Chunxiao Shen, Ziying Liu, Yiting He, Xuefei Du, Xiaorong Zhang   +8 more
wiley   +1 more source

Functionally deficient UBOX5 variants and primary angle-closure glaucoma. [PDF]

Nat Commun
Li Z, Chng WL, Liu Z, Do T, Nakano M, Chen LJ, Loo Y, Chan ASY, Topouzis F, Nongpiur ME, Ozaki M, Nakano S, Kubota T, Perera SA, Husain R, Wong TTL, Cheng CY, Ho CL, Abu-Amero K, Wong HT, Melo MB, Hien NDTN, Van Trinh N, Huong NTT, Azhany Y, Perez-Grossmann R, Chan PP, Stuart KV, Biradar MI, Szabo A, Anastasopoulos E, Giannoulis DA, Ntonti P, Papakonstantinou E, Lambropoulos A, Chatzikyriakidou A, Kilintzis V, Ayub H, Micheal S, Aung YY, Leuenberger EU, Fea A, Mon NN, Anajao A, Bi X, Kok YJ, Chong RS, Boey PY, Tan DZJ, Sin WWL, Chowbay B, Khaing CC, Aung YM, Reyes RD, Panagiotou ES, Mikropoulos DG, Voudouragkaki IC, Panos GD, Xie Z, Chen XY, Lim YT, Meah WY, Lee YS, Ho CEH, Yeo PMX, Ikeda Y, Tokuda Y, Tanaka M, Omi N, Ueno M, de Vasconcellos JPC, Costa VP, Abe RY, de Souza BB, Fong GB, Castro VV, Fujita R, Guevara-Fujita ML, Akhtar F, Ali M, Catacutan MAT, Felarca IR, Liao CS, Lavia C, Than HM, Oo KT, Soe-Kyaw PP, Frezzotti P, Pasutto F, Quino R, Minn-Din Z, Oo NL, Dallorto L, Set SH, Doan VH, Qamar R, Neto JM, Al-Obeidan S, Tham CC, Mori K, Sotozono C, Kinoshita S, Konstas AG, Liza-Sharmini AT, Zenteno JC, Do NH, Foster PJ, Tashiro K, Pang CP, Khawaja AP, Aung T, Wang Z, Khor CC.   +112 more
europepmc   +1 more source

Ocular Adverse Events Associated With Antidepressants: A Large‐Scale Data Analysis From the FAERS Database

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This decadal FAERS study (2015–2024) identifies 62,020 ocular adverse events (AEs) across 39 antidepressants, highlighting ocular neuromuscular disorders as a key risk. NDDIs show the strongest associations, while SSRIs exhibit the broadest signal spectrum.
Yiming Peng, Yichen Cao, Hanhan Liu, Junlong Ma, Guoping Yang   +4 more
wiley   +1 more source

Case report on the efficacy of phacoemulsification combined with goniosynechialysis in the treatment of advanced primary angle-closure glaucoma complicated with cataract. [PDF]

Medicine (Baltimore)
Wang Q, Zhao J.
europepmc   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes, Wioleta M. Zelek, Leendert A. Trouw   +2 more
wiley   +1 more source

Efficacy and safety of PEI combined with goniosynechialysis and goniotomy in the treatment of acute primary angle closure glaucoma. [PDF]

BMC Ophthalmol
Liu Z, Yihua Y, Hongqi J, Ting S, Qian Z, Xiaohui W, Jianhui Z.   +6 more
europepmc   +1 more source

Capillary Electrophoresis With Amperometric Detection for Neurotransmitter Analysis: Principles, Electrode Materials, Methodologies, and Applications

ELECTROPHORESIS, Volume 47, Issue 6, Page 450-478, June 2026.
This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň, Jiří Volánek, Nguyen Thi Thu Trang, Tran Dai Lam   +3 more
wiley   +1 more source

Iris cerclage with goniosynechialysis and canalicular stent for neovascular angle closure glaucoma. [PDF]

Am J Ophthalmol Case Rep
Mahjabin F, Libre PE.
europepmc   +1 more source