Results 41 to 50 of about 32,538 (267)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

Bilateral Angle-Closure Glaucoma in a Young Female Receiving Cabergoline: A Case Report

open access: yesCase Reports in Ophthalmology, 2011
Purpose: To report a case of bilateral acute angle-closure glaucoma after oral administration of cabergoline for the treatment of galactorrhea. Methods: A diagnosis of secondary drug-induced angle-closure glaucoma was made in a patient with elevated ...
Hasan Razmjoo   +4 more
doaj   +1 more source

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

open access: yes, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio   +6 more
core   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Bilateral acute angle-closure glaucoma following tramadol subcutaneous administration

open access: yesBMC Ophthalmology, 2018
Background To report a case of bilateral acute angle closure-glaucoma following the use of subcutaneous Tramadol. Case presentation A 42-year-old healthy man with unremarkable past medical and ocular history, was admitted to the Orthopedic Department for
Anis Mahmoud   +5 more
doaj   +1 more source

Unilateral chronic angle-closure glaucoma in a pediatric patient with neurofibromatosis: a case report

open access: yesJournal of International Medical Research, 2023
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease that causes multi-system damage. It is rarely associated with angle-closure glaucoma, especially in pediatric patients.
Mingming Jiang   +4 more
doaj   +1 more source

Vertical Macular Asymmetry Measures Derived From SD-OCT for Detection of Early Glaucoma. [PDF]

open access: yes, 2017
PurposeTo test the hypothesis that vertical asymmetry in macular ganglion cell/inner plexiform layer (GCIPL) thickness can improve detection of early glaucoma.MethodsSixty-nine normal eyes and 101 glaucoma eyes had macular imaging with spectral-domain ...
Afifi, Abdelmonem A   +7 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Hydrochlorothiazide Sensitised Acetazolamide induced Bilateral Angle Closure Glaucoma with Choroidal Detachment after Cataract Surgery [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Sulfonamide (Sulfa) derived medications causing bilateral secondary angle closure glaucoma with choroidal effusion is a known but rare clinical entity.
Chitaranjan Mishra   +4 more
doaj   +1 more source

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

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