Results 201 to 210 of about 16,906 (266)

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source

"Beyond the bubble"-a mixed-methods evaluation of an online psychosocial pilot program for caregivers of children with life-threatening food allergies. [PDF]

J Pediatr Psychol
Bertalan E, Horváth Z, Vadon NB, Tóth EÁ, Tóth C, Lázár AZ, Csáki C, Magyaródi T, Rigó A.   +8 more
europepmc   +1 more source

Lung maneuvers of large amplitudes for probing physiological alterations in mouse models of asthma

Animal Models and Experimental Medicine, EarlyView.
Lung maneuvers of small amplitudes, such as the ones performed in oscillometry, are the current gold standard to probe lung mechanics in animals, but they are insensitive to detect baseline physiological alterations in mouse models of asthma. Herein, lung maneuvers of different amplitudes were compared in two mouse models of asthma.
Magali Boucher, Cyndi Henry, Marie‐Josée Beaulieu, Andrés Rojas‐Ruiz, Ynuk Bossé   +4 more
wiley   +1 more source

Effects of eye closure on the spiking activity of human lateral geniculate neurons. [PDF]

Nat Commun
Self MW, Vilela-Filho O, Neuenschwander S, Silva-Filho HF, Goulart LC, Roelfsema PR.   +5 more
europepmc   +1 more source

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

Annals of Neurology, EarlyView.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey‐Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph N. Martins, Colin L. Masters, James D. Doecke, for the Alzheimer's Disease Neuroimaging Initiative   +29 more
wiley   +1 more source

Spatial Guidance Overrides Dynamic Saliency in VR: An Eye-Tracking Study on Gestalt Grouping Mechanisms and Visual Attention Patterns. [PDF]

J Eye Mov Res
Zou Q, Zheng W, Jiang X, Li D.
europepmc   +1 more source

Brief psychodynamic-interpersonal therapy for adults with a history of self-harm: the SafePIT RCT.

Health Technol Assess
Guthrie E, Copsey B, Wright-Hughes A, Dowse A, Bojke C, Mattock R, Day F, Horrocks J, Bianco G, Brennan C, McAdam M, Crawford M, Kapur N, Fernandez C, Bijsterveld P, Farrin A.   +15 more
europepmc   +1 more source

Grieving in virtual worlds: emotional processes and generational differences in avatar-based memorials on VRChat. [PDF]

Front Psychol
Fu M, Xiao H, Ruan H, Lin Y, Dong X.
europepmc   +1 more source

The journey through disruptive loss and transformational gain: a co-creative single case study on writing and publishing after psychosis. [PDF]

Philos Ethics Humanit Med
Brijs E, Walravens D, Taels L, Vanheule S.   +3 more
europepmc   +1 more source

Advances in the prevention and prenatal treatment of spina bifida. [PDF]

Discoveries (Craiova)
Sluzala ZB, Furth KE.
europepmc   +1 more source