Results 71 to 80 of about 1,618,350 (303)

Exploring the impact of chaos engineering with various user loads on cloud native applications: an exploratory empirical study

Computing
One of the most popular models that provide computer resources today is cloud computing. Today’s dynamic and successful platforms are created to take advantage of various resources available from service providers.
Amro Al-Said Ahmad, L. Al-Qora'n, Ahmad Zayed   +2 more
semanticscholar   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Design and Implementation of CMA Big Data and Cloud Platform

应用气象学报
The intensive development of meteorological operational systems and the reform of "cloud + end" technology framework are important measures to achieve high-quality development of meteorological services.
Xiao Wenming, He Wenchun, Huo Qing, Gao Feng, Xue Lei, Ni Xuelei, Wang Qi, Xiao Weiqing, Wang Ying, Wang Shu, Liu Xin, Chen Shiwang, Zhou Weiwei   +12 more
doaj   +1 more source

NFV and SDN - Key Technology Enablers for 5G Networks

, 2017
Communication networks are undergoing their next evolutionary step towards 5G. The 5G networks are envisioned to provide a flexible, scalable, agile and programmable network platform over which different services with varying requirements can be deployed
Bredel, Michael, Schaller, Sibylle, Schneider, Fabian, Yousaf, Faqir Zarrar   +3 more
core   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Performance Optimization Across the Edge-Cloud Continuum: A Multi-agent Rollout Approach for Cloud-Native Application Workload Placement

SN Computer Science
The advancements in virtualization technologies and distributed computing infrastructures have sparked the development of cloud-native applications. This is grounded in the breakdown of a monolithic application into smaller, loosely connected components,
P. Soumplis, Georgios Kontos, Panagiotis C. Kokkinos, A. Kretsis, Sergio Barrachina-Muñoz, Rasoul Nikbakht, J. Baranda, Miquel Payaró, J. Mangues-Bafalluy, Emmanuel Varvarigos   +9 more
semanticscholar   +1 more source

Cloudnativesim: A Toolkit for Modeling and Simulation of Cloud‐Native Applications [PDF]

Software, Practice & Experience
Cloud‐native applications are increasingly becoming popular in modern software design. Employing a microservice‐based architecture into these applications is a prevalent strategy that enhances system availability and flexibility.
Jingfeng Wu, Minxian Xu, Yiyuan He, Kejiang Ye, Cheng-zhong Xu   +4 more
semanticscholar   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

Advanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin, Jovanne Palvair, Lennie Messager, Jamal Bamoulid, Jasper Callemeyn, Mélanie Chaintreuil, Ludivine Dal Zuffo, Didier Ducloux, Imane Farhat, Mathieu Legendre, Laurent Martin, Florian Renosi, Xavier Roussel, Thibaut Vaulet, Maarten Naesens, Claire Tinel, Baptiste Lamarthée   +16 more
wiley   +1 more source

Architecture for Analysis of Streaming Data

, 2018
While several attempts have been made to construct a scalable and flexible architecture for analysis of streaming data, no general model to tackle this task exists.
Hoque, Sheik, Miranskyy, Andriy
core   +1 more source