Results 71 to 80 of about 21,516 (235)

Intramolecular N···F Pnictogen Bond Mitigates the Explosive Behavior of Azido‐L‐Phenylalanines

ChemistryEurope, EarlyView.
An intramolecular N···F pnictogen bond is the key for the chemical stabilization of the fluorinated azido‐L‐phenylalanines, mitigating the risk of explosion and thus facilitating the handling and storage of these materials. Organic azides are versatile intermediates but are plagued by intrinsic instability and potential explosiveness. Here, it is shown
Andrea Pizzi, Eleonora Veronese, Nicola Demitri, Marco Saccone, Pierangelo Metrangolo, Giancarlo Terraneo   +5 more
wiley   +1 more source

Research on multi-dimensional reconstruction mechanism of cloud native full link in the metaverse scenario. [PDF]

Sci Rep, 2023
Sheng S.
europepmc   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

Cytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas, Yang Yue, Morgan L. Pimm, Takashi Hotta, Ryoma Ohi, Kristen J. Verhey   +5 more
wiley   +1 more source

Availability, Scalability, and Security in the Migration from Container-Based to Cloud-Native Applications

Computers
The shift from traditional monolithic architectures to container-based solutions has revolutionized application deployment by enabling consistent, isolated environments across various platforms.
Bruno Nascimento, Rui Santos, João Henriques, Marco V. Bernardo, Filipe Caldeira   +4 more
doaj   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

The scaling of seed‐dispersal specialization in interaction networks across levels of organization

Ecography, EarlyView.
Natural ecosystems are characterized by a specialization pattern where few species are common while many others are rare. In ecological networks involving biotic interactions, specialization operates as a continuum at individual, species, and community levels. Theory predicts that ecological and evolutionary factors can primarily explain specialization.
Gabriel M. Moulatlet, Pedro Luna, Wesley Dáttilo, Fabricio Villalobos   +3 more
wiley   +1 more source

Data integration advances reproductive phenology research across temporal, spatial and taxonomic scales

Ecography, EarlyView.
Climate change is altering plant reproductive phenology; however, a scarcity of long‐term, systematic monitoring hinders our ability to quantify and predict these responses in many parts of the world. We addressed this gap by demonstrating how data integration can be used to produce a synthesised record of reproductive phenology observations (flowering
Ella Cathcart‐van Weeren, John M. Dwyer, Brian Hawkins, Jennifer Holmes, Glenn Holmes, Glenn Leiper, William McDonald, Matthew Mo, Hugh Nicholson, Rob Price, Karen Shaw, Spencer Shaw, David Waterhouse, Lui Weber, Matthew S. Luskin   +14 more
wiley   +1 more source

A call for ethical, equitable, and effective artificial intelligence to improve care for all people with epilepsy: A roadmap. A report by the ILAE Global Advocacy Council and Big Data Commission

Epilepsia, EarlyView.
Abstract The artificial intelligence (AI) revolution is upon us. It will inevitably form a central component of epilepsy workflows and patient advocacy. Therefore, it behooves us as health care providers to ride the crest of this wave and guide its direction for the benefit of all people with epilepsy.
Colin B. Josephson, Sandor Beniczky, Spiros Denaxas, Akio Ikeda, Lara Jehi, Angelina Kakooza Mwesige, Nathalie Jette, Gabriel Davis Jones, Philippe Ryvlin, Arjune Sen, Chahnez Charfi Triki, Gabriella Waters, Alla Guekht, J. Helen Cross   +13 more
wiley   +1 more source

Big Data Access Control for Cloud-Native Hadoop Environments

Journal of Communications Software and Systems
The rise of Big Data necessitates robust access control for platforms like Hadoop. While traditionally deployed on physical servers within trusted networks, Hadoop is increasingly migrating to cloud-native, containerized environments.
Fidele Tsognong, Benoit Martin Azanguezet Quimatio, Marcellin Julius Nkenlifack   +2 more
doaj   +1 more source