The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Autonomous vehicles with augmented reality internet of things and edge intelligence system for industry 5.0 based on 6G. [PDF]
Ahmed AA +9 more
europepmc +1 more source
Comment on “De Novo Reconstruction of 3D Human Facial Images from DNA Sequence”
This comment examines AI‐driven DNA‐based facial reconstruction, focusing on the Difface model. While such technologies promise biomedical and forensic applications, they pose significant ethical, legal, and methodological challenges. We emphasize transparency, benchmarking, and rigorous validation to avoid misinterpretation and misuse.
Jennifer K. Wagner +3 more
wiley +1 more source
Snow cover mapping with Meteosat third generation FCI: initial evaluation of the European Organisation for the Exploitation of Meteorological Satellites H SAF H43 snow mask product. [PDF]
Kuter S +3 more
europepmc +1 more source
Learned Conformational Space and Pharmacophore Into Molecular Foundational Model
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang +8 more
wiley +1 more source
AI-Enabled Dynamic Edge-Cloud Resource Allocation for Smart Cities and Smart Buildings. [PDF]
Dumitru MC +4 more
europepmc +1 more source
This study presents a novel in situ laser‐induced breakdown spectroscopy system for monitoring metal vapors produced by the intense laser‐metal interactions in laser powder bed fusion additive manufacturing and laser welding. The insights from this new technique reveal changes in alloy compositions and provide the first in situ validation of multi ...
Anna C. M. Getley +8 more
wiley +1 more source
Sensor Driven Resource Optimization Framework for Intelligent Fog Enabled IoHT Systems. [PDF]
Khan S +5 more
europepmc +1 more source
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang +11 more
wiley +1 more source
Identifying and assessing the cloud computing implementation drivers for sustainable building projects. [PDF]
Alkersh M, Alhusban M.
europepmc +1 more source

