Results 51 to 60 of about 1,202,853 (260)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Multivariate time series collaborative compression for monitoring systems in securing cloud-based digital twin

Journal of Cloud Computing: Advances, Systems and Applications
With the booming of cloud-based digital twin systems, monitoring key performance indicators has become crucial for ensuring system security and reliability.
Zicong Miao, Weize Li, Xiaodong Pan
doaj   +1 more source

Security of Cloud FPGAs: A Survey [PDF]

arXiv, 2020
Integrating Field Programmable Gate Arrays (FPGAs) with cloud computing instances is a rapidly emerging trend on commercial cloud computing platforms such as Amazon Web Services (AWS), Huawei cloud, and Alibaba cloud. Cloud FPGAs allow cloud users to build hardware accelerators to speed up the computation in the cloud.
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Temporal enhanced sentence-level attention model for hashtag recommendation

CAAI Transactions on Intelligence Technology, 2018
Hashtags of microblogs can provide valuable information for many natural language processing tasks. How to recommend reliable hashtags automatically has attracted considerable attention.
Jun Ma, Chong Feng, Ge Shi, Xuewen Shi, Heyang Huang   +4 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

A review of enhanced biosignature immunotherapy tools for predicting lung cancer immune phenotypes using deep learning

Discover Oncology
Cancer has increasingly been recognized as a genetic disease, influenced by lifestyle changes, dietary patterns, and environmental pollutants. Lung cancer remains one of the most lethal malignancies worldwide, necessitating precise diagnostic and ...
A. Sheryl Oliver, Md Shohel Sayeed, Siti Fatimah Abdul Razak   +2 more
doaj   +1 more source

Service Management for IoT: Requirements, Taxonomy, Recent Advances and Open Research Challenges

IEEE Access, 2019
The exponential growth in the number of smart devices connected to the Internet of Things (IoT), and associated with various IoT-based smart applications and services, raises interoperability challenges which could affect the sustainability of IoT ...
Abdelmuttlib Ibrahim Abdalla Ahmed, Abdullah Gani, Siti Hafizah Ab Hamid, Abdelzahir Abdelmaboud, Hassan Jamil Syed, Riyaz Ahamed Ariyaluran Habeeb Mohamed, Ihsan Ali   +6 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Lightweight Multiscale Spatio-Temporal Graph Convolutional Network for Skeleton-Based Action Recognition

Big Data Mining and Analytics
Using skeletal information to model and recognize human actions is currently a hot research subject in the realm of Human Action Recognition (HAR). Graph Convolutional Networks (GCN) have gained popularity in this discipline due to their capacity to ...
Zhiyun Zheng, Qilong Yuan, Huaizhu Zhang, Yizhou Wang, Junfeng Wang   +4 more
doaj   +1 more source