The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang +15 more
wiley +1 more source
Characterizing core outcomes of responsible stewardship for human genomic data in the cloud. [PDF]
Rahimzadeh V +4 more
europepmc +1 more source
The strengthened EMSI in Pd/CoN‐Co4N induces electronic rearrangement, generating abundant Pd0 species in situ, modulating the Pd d‐band center to enhance O2 adsorption and MEK activation. Concurrently, it creates numerous Lewis acid sites that preferentially adsorb poisons and shield the active sites.
Yadi Wang +7 more
wiley +1 more source
Cloud-to-Edge Deployment of Optimized nnU-Net for Ischemic Stroke Lesion Segmentation on Resource-Constrained Embedded Devices. [PDF]
Alcaraz-Ortiz D +2 more
europepmc +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
Non-destructive and accurate phenotypic detection method for okra seedlings under salt stress based on dual-view feature fusion and lightweight PointNet+. [PDF]
Liu S +10 more
europepmc +1 more source
Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram +4 more
wiley +1 more source
Interpreting the dominant signature of inhomogeneous mixing resulting from dry-air entrainment in clouds. [PDF]
Allwayin N +6 more
europepmc +1 more source
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou +4 more
wiley +1 more source
The cell cloud: Adopting systems biology concepts in the era of single-cell immunology. [PDF]
Shay T, Benoist CO, Grieshaber-Bouyer R.
europepmc +1 more source

