Results 81 to 90 of about 1,530,762 (291)

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Cloud native based lightweight 5GC product and key technologies

open access: yesDianxin kexue, 2020
With the development of 5G,the 5G private network enables the industry and shows great market opportunities.Lightweight 5G core products based on cloud native are the most important components of the 5GC private network.Lightweight 5G core products,using
Changyi CHEN   +4 more
doaj  

Saint Cloud Reporter [February 1970] [PDF]

open access: yes, 1970
Saint Cloud Reporter, February 1970https://repository.stcloudstate.edu/magazines/1123/thumbnail ...
St. Cloud State University
core  

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

open access: yesAdvanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu   +14 more
wiley   +1 more source

Optimizing UE Power Efficiency: AI/ML Approach for Upgrade Time Determination

open access: yesIEEE Access
The transition of Control Plane (CP) block functions into software entities, as proposed by 3GPP, necessitates periodic downtime for maintenance activities such as software upgrades or failures.
Karthikeyan Subramaniam   +4 more
doaj   +1 more source

An industrial internet business management platform that supports the cloud-native

open access: yesDianxin kexue, 2022
Aiming at the trend of industrial enterprises facing the evolution from the traditional business management information architecture to the cloud-native platform management, an evolutionary architecture of the transitional industrial internet business ...
Wenzhe WANG   +8 more
doaj  

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

Core idea、technical architecture and strategic significance of “5G+” system

open access: yesDianxin kexue, 2020
Based on the investigation of digital native evolution and case analysis,the concept framework of “5G+native” was put forward to describe the application scenarios and enterprises highly dependent on 5G high-performance network connection,its core idea ...
Kang CAI, Xiaohong LIAO, Hua TAN
doaj  

Cloud Services Brokerage : a survey and research roadmap [PDF]

open access: yes, 2015
A Cloud Services Brokerage (CSB) acts as an intermediary between cloud service providers (e.g., Amazon and Google) and cloud service end users, providing a number of value adding services. CSBs as a research topic are in there infancy.
Barker, Adam David   +6 more
core   +1 more source

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