Results 81 to 90 of about 67,019 (264)

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

open access: yesAdvanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu   +12 more
wiley   +1 more source

Scheme of Smart Home Application Control Based on Cloud Service

open access: yesDianxin kexue, 2015
How smart home devices access network,how intelligent control terminals control the smart home equipment,and how smart home devices and application management platform manage users and devices,all the solutions of these problems are changing with the ...
Bin Wang, Xiaoling Yang, Dongdi Xiao
doaj  

A multi-agent system approach for trustworthy cloud service discovery

open access: yesCogent Engineering, 2016
Harnessing the benefits of cloud computing, demands that a potential user has adequate access to trustworthy cloud services. Locating resources and services in a heterogeneous network such as cloud environment may be a tedious task.
A.O. Akinwunmi   +2 more
doaj   +1 more source

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

Algorithm for the cloud service workflow scheduling with setup time and deadline constraints

open access: yesTongxin xuebao, 2015
Cost minimization with deadline constraints and setup time is a new resource allocation optimization problem in cloud computing.An integer programming model is constructed for this NP-hard problem.A novel probability model and updating mechanism is ...
Hong SHEN, Xiao-ping LI
doaj  

Adaptive Multi-Level Cloud Service Selection and Composition Using AHP–TOPSIS

open access: yesApplied Sciences
The growing diversity of cloud services has made evaluating their relative merits in terms of price, functionality, and availability increasingly complex, particularly given the wide range of deployment alternatives and service capabilities.
V. N. V. L. S. Swathi   +2 more
doaj   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

A Study on Strategic Provisioning of Cloud Computing Services

open access: yesThe Scientific World Journal, 2014
Cloud computing is currently emerging as an ever-changing, growing paradigm that models “everything-as-a-service.” Virtualised physical resources, infrastructure, and applications are supplied by service provisioning in the cloud.
Md Whaiduzzaman   +3 more
doaj   +1 more source

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