Results 201 to 210 of about 2,016,098 (294)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Biobased Boston Ivy‐Inspired Cryogel Integrating Radiative Cooling and Phase Change Energy Storage for Adaptive Thermal Regulation

open access: yesAdvanced Science, EarlyView.
A bionic cryogel containing phase‐change materials that provides daytime radiative cooling and nighttime heat release is developed to promote environmentally sustainable and comfortable housing and living environments with reduced building energy demand.
Sining Huang   +6 more
wiley   +1 more source

Quenching Photo‐Induced Free Radicals Endows Superomniphobic Atmospheric Water Harvesting Hydrogels With UV Resistance for Durable Bifacial Photovoltaic Cooling

open access: yesAdvanced Science, EarlyView.
A hygroscopic hydrogel layer functionalized with fullerene C60 tackles heat and dust challenges in bifacial photovoltaics (PV) panels. It resists soiling and photo‐aging, maintains high transparency, absorbs water vapor from the air during the night, and delivers strong evaporative cooling power during daytime, significantly lowering PV panel ...
Xiaoqi Zhou   +6 more
wiley   +1 more source

Isolated VM Storage on Clouds

open access: yesIEICE Transactions on Information and Systems, 2015
SEOL, Jinho   +2 more
openaire   +3 more sources

Mechanism of Direct Acoustic Construction and Gradient Properties Tuning

open access: yesAdvanced Science, EarlyView.
Directed acoustic construction enables omnidirectional gradient tuning of fingerprint‐inspired microstructures. By investigating the DAC mechanisms, diamond particles are found to enhance acoustic physical, mechanical, and chemical effects, promoting acoustic curing and broadening the range of gradient property tuning.
Dandan Wu   +6 more
wiley   +1 more source

An Explainable Multimodal Deep‐Learning Model Using Histopathological Image and Clinical Information for Prognosis Prediction in Colorectal Cancer: A Multi‐Center Cohort Study

open access: yesAdvanced Science, EarlyView.
This study develops a multimodal deep‐learning model that integrates clinical variables and histopathological images to predict survival outcomes in colorectal cancer. The multimodal model effectively stratifies patients into low‐ and high‐risk groups, demonstrating superior accuracy and generalizability across multiple independent cohorts.
Zhihan Jiang   +12 more
wiley   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

open access: yesAdvanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu   +8 more
wiley   +1 more source

Emerging Memory and Device Technologies for Hardware‐Accelerated Model Training and Inference

open access: yesAdvanced Electronic Materials, EarlyView.
This review investigates the suitability of various emerging memory technologies as compute‐in‐memory hardware for artificial intelligence (AI) applications. Distinct requirements for training‐ and inference‐centric computing are discussed, spanning device physics, materials, and system integration.
Yoonho Cho   +6 more
wiley   +1 more source

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