Results 231 to 240 of about 13,943,822 (340)

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

Cloud-native simulation framework for gossip protocol: Modeling and analyzing network dynamics. [PDF]

PLoS One
Wira SS, Tan CK, Wong WP, Tan IKT.
europepmc   +1 more source

From Code to Life: The AI‐Driven Revolution in Genome Editing

Advanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li, Wasi Ullah Khan, Genxiang Bai, Chao Dong, Jungang Wang, Youpeng Zhang, Chong Wang, Hongbin Zhang, Wenyi Wang, Ming Luo, Fei Chen   +10 more
wiley   +1 more source

Diagnostic Accuracy of the Alice NightOne Single-Belt Monitor for Obstructive Sleep Apnea and Reliability of Wireless Data Transfer. [PDF]

Nat Sci Sleep
Peng M, Zhang Y, Zhao R, Li J, Zhang X, Deng L, Zhao L, Zhou B, Wang X, Dong X, Han F.   +10 more
europepmc   +1 more source

Poster: A Procedure for Testing Applications Through Cloud Computing Elasticity

, 2016
Michel Albonico, Jean‐Marie Mottu, Gerson Sunyé   +2 more
openalex   +1 more source

Unassisted Switchable Dual‐Photoelectrode Devices Utilizing p‐n Carbon Quantum Dots as “Semiconductor Electrolytes”: Optimization Between H2O2 and Solar Electricity Production

Advanced Science, EarlyView.
p‐n type carbon quantum dots (N‐CQDs) are designed as a conceptually‐new “semiconductor electrolyte” to develop a self‐driven photoelectrochemical cell that can be switched to optimize between H2O2 production and electricity generation under visible‐light illumination with water and O2 as reaction reagents.
Hui‐Min Duan, Chen‐Guang Li, Liu‐Meng Mo, Jing‐Shuang Dang, Xiao‐Hui Jia, Jia‐Cheng Yu, Yu‐Hang Mei, Anders Thapper, Hong‐Yan Wang   +8 more
wiley   +1 more source

A machine learning based authentication and intrusion detection scheme for IoT users anonymity preservation in fog environment. [PDF]

PLoS One
Oliullah K, Whaiduzzaman M, Mahi MJN, Jan T, Barros A.   +4 more
europepmc   +1 more source

BrainFusion: a Low‐Code, Reproducible, and Deployable Software Framework for Multimodal Brain‒Computer Interface and Brain‒Body Interaction Research

Advanced Science, EarlyView.
BrainFusion is a low‐code software framework for multimodal brain–computer interface (BCI)​​ and brain–body interaction research. It supports ​electroencephalography (EEG)​, functional near‐infrared spectroscopy (fNIRS), electromyography (EMG)​, and electrocardiography (ECG)​​ integration with standardized preprocessing, feature fusion, and model ...
Wenhao Li, Chenyang Gao, Zhaobo Li, Yunheng Diao, Jiaxin Li, Jiayi Zhou, Jing Zhou, Ying Peng, Guanchu Chen, Xuecheng Wu, Kai Wu   +10 more
wiley   +1 more source

A secured remote patient monitoring framework for IoMT ecosystems. [PDF]

Sci Rep
Bhattacharya P, Mukherjee A, Bhushan B, Gupta SK, Gadekallu TR, Zhu Z.   +5 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment

Advanced Science, EarlyView.
This study uses single‐nucleus RNA sequencing and spatial transcriptomics to investigate penile squamous cell carcinoma (PSCC). It reveals that PSCC tumor cells mimic normal penile epithelium differentiation, independent of HPV status. The Tum_1 subtype shows basal stem‐like characteristics and promotes invasiveness. HPV‐positive basal stem‐like tumors
Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu   +37 more
wiley   +1 more source