Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Clouds and the Near-Earth Environment: Possible Links
Climate variability is a hot topic not only for scientists and policy-makers, but also for each and every one of us. The anthropogenic activities are considered to be responsible for most climate change, however there are large uncertainties about the ...
Condurache-Bota Simona +2 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Telemedicine in civil protection: A controlled simulation study for the analysis of patient care
Objectives More and more disasters are occurring and there will be an increasing shortage of physicians in the future. Telemedicine could be a solution here to offer medical care despite the lack of physicians in the area of operation.
Anna Müller +6 more
doaj +1 more source
Application of MODIS Products for Air Quality Studies Over Southeastern Italy
Aerosol optical thicknesses (AOTs) by the MODerate Resolution Imaging Spetroradiometer (MODIS) on-board Aqua and Terra satellites, and ground-based measurements of PM10 mass concentrations, collected over three years (2006–2008) at two suburban sites ...
Maria Rita Perrone +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Evaluation and Normalization of Cloud Obscuration Related BRDF Effects in Field Spectroscopy
The impact of target bidirectional reflectance in dual field of view spectroscopy was described and quantified using field measurements and ray-tracing simulations.
Jan Stuckens +4 more
doaj +1 more source
Global Distribution of Clouds over Six Years: A Review Using Multiple Sensors and Reanalysis Data
A six-year global study of cloud distribution and cloud properties obtained from observations of the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO), the Atmospheric Infrared Sounder (AIRS), and the Modern-Era Retrospective ...
Lerato Shikwambana
doaj +1 more source
Looking for the rainbow on exoplanets covered by liquid and icy water clouds
Looking for the primary rainbow in starlight that is reflected by exoplanets appears to be a promising method to search for liquid water clouds in exoplanetary atmospheres. Ice water clouds, that consist of water crystals instead of water droplets, could
Hovenier, J. W. +2 more
core +2 more sources
GASS High Velocity Clouds in the Region of the Magellanic Leading Arm [PDF]
We present a catalog of high-velocity clouds in the region of the Magellanic Leading Arm. The catalog is based on neutral hydrogen (\HI) observations from the Parkes Galactic All-Sky Survey (GASS).
Begum +31 more
core +1 more source

