Results 51 to 60 of about 1,144,906 (160)
Severe acute liver disease in adults: Contemporary role of histopathology
Histopathology, Volume 85, Issue 4, Page 549-561, October 2024.This overview provides an insight into the contemporary role of biopsies (as well as explant and autopsy material) in diagnosing acute liver disease. It outlines up‐to‐date clinical definitions of liver injury and considers recent recommendations for the diagnosis of AIH and drug‐induced, autoimmune‐like hepatitis (DI‐AIH).
Andrew D Clouston +19 more
wiley +1 more source
Comparative analysis of gene and disease selection in genomic newborn screening studies
Journal of Inherited Metabolic Disease, Volume 47, Issue 5, Page 945-970, September 2024.Abstract Genomic newborn screening (gNBS) is on the horizon given the decreasing costs of sequencing and the advanced understanding of the impact of genetic variants on health and diseases. Key to ongoing gNBS pilot studies is the selection of target diseases and associated genes to be included.
Isabel R. Betzler +8 more
wiley +1 more source
Journal of Dermatological TreatmentPurpose We aim to explore a potential treatment strategy for hair loss.Materials and methods A male 6-year-old child was diagnosed with hidrotic ectodermal dysplasia 2 (HED2) caused by GJB6 (p.G11R) mutations.
Shiyi Zhong +5 more
doaj +1 more source
Obesity Science &Practice, Volume 10, Issue 1, February 2024.The World Trade Center disaster rescue workers and other responders continue to bear the burden of multiple co‐morbidities, including metabolic syndrome, cardiovascular disease, systemic inflammation, and post‐traumatic stress disorder (PTSD). This study describes the findings of a pilot randomized controlled trial assessing the feasibility of a ...
Chrisa Arcan +7 more
wiley +1 more source
The FASEB Journal, Volume 38, Issue 1, 15 January 2024.MicroRNA (miRNA)‐155 is elevated in EoE patient esophagi. MiR‐155 localization using in situ hybridization shows predominantly basal epithelial expression. Epithelial miR‐155 activity was evident through diminished target gene expression, particularly in relatively undifferentiated basal cell states. MiR‐155 stable overexpression induced a functionally
Gary E. Markey +5 more
wiley +1 more source
Detailed Analysis of ITPR1 Missense Variants Guides Diagnostics and Therapeutic Design
Movement Disorders, Volume 39, Issue 1, Page 141-151, January 2024.Abstract Background The ITPR1 gene encodes the inositol 1,4,5‐trisphosphate (IP3) receptor type 1 (IP3R1), a critical player in cerebellar intracellular calcium signaling. Pathogenic missense variants in ITPR1 cause congenital spinocerebellar ataxia type 29 (SCA29), Gillespie syndrome (GLSP), and severe pontine/cerebellar hypoplasia.
Jussi Pekka Tolonen +48 more
wiley +1 more source
Occupational Therapy International, Volume 2024, Issue 1, 2024.Introduction: Poor fit between the work environment and work expectations is associated with high levels of workplace‐related stress. Work stress in occupational therapy has been attributed to the nature of the profession and various other workplace‐related factors. Workplace‐related stress leading to burnout has been found to be higher in early career
Patricia de Witt +4 more
wiley +1 more source
Supplemental material for Pearls of wisdom: using the single case study or ‘gem’ to identify strategies for mediating stress and work-life imbalance in healthcare staff [PDF]
, 2019 Supplemental Material for Pearls of wisdom: using the single case study or ‘gem’ to identify strategies for mediating stress and work-life imbalance in healthcare staff by Teena J Clouston in Journal of Research in ...
Teena J Clouston (6717524) +1 more
core +1 more source
The oral mucosal and salivary microbial community of Behçet's syndrome and recurrent aphthous stomatitis. [PDF]
, 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is ...
Bergmeier, LA +9 more
core +1 more source
Binding in Nominal Equational Logic [PDF]
, 2010 Many formal systems, particularly in computer science, may be expressed through equations modulated by assertions regarding the 'freshness of names'. It is the presence of binding operators that make such structure non-trivial.
Ranald Clouston, Clouston, Ranald
core +1 more source